Effectiveness of Herbal Medicine in Renal Lithiasis: a Review
DOI:
https://doi.org/10.33192/Smj.2020.25Keywords:
Renal lithiasis; pharmacology; therapeutic; herbal medicineAbstract
The renal lithiasis is a frequent disease that affect between 4-15% of worldwide population with a high percentage of recurrences. The composition of the stone is variated, but, more than 80% of uroliths are of calcium oxalate. The mechanisms involved in the formation of calcific stones are not fully understood and the available treatment not permit the prevention and destruction of the stones at same time. For these reasons, many studies have been focused to understand the mechanism involved in the renal lithiasis and in the development the new drugs for the treatment and prevention of this pathology and its recurrences. In this paper, it is shown a review about formation of calcific stones, their treatment and the effectiveness of the herbal medicine as alternative treatment. Also, a list of antilithiatic remedies of cuban herbal medicine is showed.
References
1. Grases F, Costa-Bauza A, Prieto RM. Renal lithiasis and nutrition. Nutrition Journal 2006;5:23-29.
2. Aggarwal KP, Tandon S, Naik PK, Singh SK, Tandon C. Novel antilithiatic cationic proteins from human calcium oxalate renal stone matrix identified by MALDI-TOF-MS endowed with cytoprotective potential: An insight into the molecular mechanism of urolithiasis. Clinica Chimica Acta 2013;415:181-90.
3. Torres C, Grases F, Rodrigo D, García AM, Gómez C, Frontera G. Risk factors for urinary stones in healthy schoolchildren with and without a family history of nephrolithiasis. Pediatr Nephrol 2013;28:639-45.
4. Cook J, Lamb BW, Lettin JE, Graham SJ. The epidemiology of urolithiasis in an ethnically diverse population living in the same area. Urol J 2016;13:2754-8.
5. Mittal A, Tandon S, Singla SK, Tandon C. In vitro inhibition of calcium oxalate crystallization and crystal adherence to renal tubular epithelial cells by Terminalia arjuna. Urolithiasis 2016;44:117-25.
6. Cano R, Carrasco J, Pérula LA, Jiménez C, Olaya I, Criado M, et al. Prevalence of renal stones in Andalusian population: Results of PreLiRenA study. Actas Urol Esp 2015;39:26-31.
7. Nalini HS, Manickavasakam K, Thomas MW. Prevalence and risk factors of kidney stone. GJRA 2016;5:183-7.
8. Sarroca M, Arada A. Litiasis renal. AMF 2015;11:314-23.
9. Alelign T, Petros B. Kidney stone disease: An update on current concepts. Advances in Urology 2018;2018:1-12.
10. Bashir S, Gilani AH. Antiurolithic effect of berberine is mediated through multiple pathways. Eur J Pharmacol 2011;651:168-75.
11. Rodgers AL. Physicochemical mechanism of stone formation. Urolithiasis 2017;45:27-32.
12. Grases F, Genestar C, Conte A. Inhibidores de la litiasis renal: evolución histórica, situación actual y perspectivas futuras. Medicina Clínica 1988;90:83-87.
13. Tsujihata M. Mechanism of calcium oxalate renal stone formation and renal tubular cell injury. Int J Urol 2008;15:115-20.
14. Johri N, Cooper B, Robertson W, Choong S, Rickards D, Unwin R. An update and practical guide to renal stone management. Nephron Clin Pract 2010;116:159-71.
15. Green W, Ratan H. Molecular mechanisms of urolithiasis. Urology 2013;81:701-4.
16. Sethmann I, Nordahl GW, Knoll T, Enzmann F, Simon L, Kleebe HJ. Microstructures of Randall’s plaques and their interfaces with calcium oxalate monohydrate kidney stones reflect underlying mineral precipitation mechanisms. Urolithiasis 2017;45:235-48.
17. Mirian EC, Juanita NM, Christophe BO, Estela MC. Molecular mechanisms involved in the protective effect of the chloroform extract of Selaginella lepidophylla (Hook. et Grev.) Spring in a lithiasic rat model. Urolithiasis 2013;41:205-15.
18. Vaitheeswari S, Sriram R, Brindha P, Kurian GA. Studying inhibition of calcium oxalate stone formation: an in vitro approach for screening hydrogen sulfide and its metabolites. Int Braz J Urol 2015;41:503-10.
19. Grases F, Costa-Bauzá A. Phytate (IP6) is a powerful agent for preventing calcifications in biological fluids: usefulness in renal lithiasis treatment. Anticancer Res 1999;19:3717-22.
20. González G. Litiasis renal: estudio y manejo endocrinológico. Rev Med Clin Condes 2013;24:798-803.
21. Semins MJ, Matlaga BR. Medical evaluation and management of urolithiasis. Ther Adv Urol 2010;2:3-9.
22. Arrabal-Polo MA, Arrabal-Martin M, Garrido-Gomez J. Calcium renal lithiasis: metabolic diagnosis and medical treatment. Sao Paulo Med J 2013;131:46-53.
23. Rathod NR, Biswasa D, Chitmeb HR, Ratna S, Muchandia IS, Chandra R. Anti-urolithiatic effects of Punica granatum in male rats. J Ethnopharmacol 2012;140:234-8.
24. Rodríguez NF, Pérez JA, Iglesias JC, Gallego RM, Veiga BL, Cotelo NV. Actualidad de las plantas medicinales en terapéutica. Acta Farmacéutica Portuguesa 2015;4:42-52.
25. Petrovska BB. Historical review of medicinal plants’ usage. Pharmacogn Rev 2012;6:1-5.
26. Escalona LJ, Tase A, Estrada A, Almaguer ML. Uso tradicional de plantas medicinales por el adulto mayor en la comunidad serrana de Corralillo Arriba. Guisa, Granma. Revista Cubana de Plantas Medicinales 2015;20:429-39.
27. Majouli K, Hamdi A, Hlila MB. Phytochemical analysis and biological activities of Hertia cheirifolia L. roots extracts. Asian Pac J Trop Med 2017;10:1134-9.
28. Calixto JB. Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res 2000;33:179-89.
29. Ahmed S, Mallick IA, Hasan MM. Exploring globally used antiurolithiatic plants of A to L families: Asteraceae, Fabaceae and Lamiaceae revisited. Journal of Pharmacognosy and Phytochemistry 2017;6:1780-7.
30. Ahmed S, Hasan MM. Exploring globally used antiurolithiatic plants of M to R families: Including Myrtaceae, Phyllantaceae, Piperaceae, Polygonaceae, Rubiaceae and Rutaceae. Journal of Pharmacognosy and Phytochemistry 2017;6:325-35.
31. Ahmed S, Hasan MM. Exploring globally used antiurolithiatic plants of M to R families: Including Saxifragaceae, Scrophulariaceae, Solanaceae, Urticaceae, Vitaceae, Zingiberaceae and Zygophyllaceae. Journal of Pharmacognosy and Phytochemistry 2017; 6:325-35.
32. Ahmed S, Giliani SMU, Hasan M. Antiurolithiatic potential of globally used medicinal plants belonging to the family Rosaceae. Journal of Pharmacognosy and Phytochemistry 2017;6:1028-31.
33. Ahmed S, Hasan MM. A review on globally used antiurolithiatic monoherbal formulation belonging to Boraginaceae, Brassicaceae, Malvaceae and Poaceae families. World Journal of Pharmacy and Pharmaceutical Sciences 2017;6:48-61.
34. Callejas S, Loyola O, Díaz H, López F, Rodríguez JA. Historia de Cuba. Pueblo y Educación: La Habana, 2010.p.1-6.
35. Martí J. Diario de Campaña. De Cabo Haitiano a Dos Ríos. Biblioteca Virtual Universal. Editorial del Cardo, 2003. Disponible en: http://www.biblioteca.org.ar
36. Roig JT. Plantas medicinales, aromáticas o venenosas de Cuba. Tomo I, 2da Edición. Cuba: Editorial Ciencia y Técnica, 2012. Págs.: 228-229.
37. Scull R, Miranda M, Infante R. Plantas medicinales de uso tradicional en Pinar del Río. Estudio etnobotánico. I. Rev Cubana Farm 1998;32:57-62.
38. Boffill MA. Plantas Medicinales usadas en Cuba con efecto diurético comprobado experimentalmente. Medicentro 2008;12(1). http://www.revmedicentro.sld.cu/index.php/medicentro/article/view/1183/1535
39. Beyra A, León MC, Iglesias E, Ferrándiz D, Herrera R, Volpato G, et al. Estudios etnobotánicos sobre plantas medicinales en la provincia de Camagüey (Cuba). Anales del Jardín Botánico de Madrid 2004;61:185-203.
40. Godínez D, Volpato G. Plantas medicinales que se venden en el mercado El Río, Camagüey, Cuba. Revista Mexicana de Biodiversidad 2008;79:243-259.
41. Cano JH, Volpato G. Herbal mixtures in the traditional medicine of eastern Cuba. J Ethnopharmacol 2004;90:293-316.
42. Volpato G, Godínez D, Beyra A, Barreto A. Uses of medicinal plants by Haitian immigrants and their descendants in the Province of Camaüey, Cuba. J Ethnobiol Ethnomed 2009;5:16.
43. Riverón FB, Hernández Y, García A, Escalona RY. La colección de plantas medicinales del Jardín Botánico de Holguín, Cuba: su importancia social y científica. Revista del Jardín Botánico Nacional 2015;36:219-22.
44. Bashir S, Gilani AH. Antiurolithic effect of Bergenia ligulata rhizome: an explanation of the underlying mechanisms. J Ethnopharmacol 2009;122:106-16.
45. Pérez RA, Rivas C, Ramos ML. Actividad antiurolítica. En: Rivas C, Oranday MA, Verde MJ, editors. Investigación en plantas de importancia médica. México: Omnia Science; 2016.p.161-70.
46. Pérez RA; Leos C; Oranday MA, Hernández CE, Sánchez E; Rivas C. Efecto in vitro en la inhibición del proceso de nucleación en litiasis renal, capacidad de captura de radicales libres, actividad antimicrobiana y tóxica del extracto metanólico de Berberis trifoliata. Revista Mexicana de Ciencias Farmacéuticas 2015;46:70-76.
47. Ahmed S, Hasan MM, Khan H, Mahmood ZA, Patel S. The mechanistic insight of polyphenols in calcium oxalate urolithiasis mitigation. Biomed Pharmacother 2018;106:1292-9.
48. Zeng X, Xi Y, Jiang W. Protective role of flavonoids and flavonoid-rich plant extracts against urolithiasis: A review. Food Sciences and Nutrition 2018. Available at: http://doi.org/10.1080/10408398.2018.1439880
49. Newman DJ, Cragg GM. Natural Products as Sources of New Drugs from 1981 to 2014. J Nat Prod 2016;79:629-61.
50. Butterweck V, Khan SR. Herbal Medicines in the Management of Urolithiasis: Alternative or Complementary? Planta Med 2009;75:1095-103.
2. Aggarwal KP, Tandon S, Naik PK, Singh SK, Tandon C. Novel antilithiatic cationic proteins from human calcium oxalate renal stone matrix identified by MALDI-TOF-MS endowed with cytoprotective potential: An insight into the molecular mechanism of urolithiasis. Clinica Chimica Acta 2013;415:181-90.
3. Torres C, Grases F, Rodrigo D, García AM, Gómez C, Frontera G. Risk factors for urinary stones in healthy schoolchildren with and without a family history of nephrolithiasis. Pediatr Nephrol 2013;28:639-45.
4. Cook J, Lamb BW, Lettin JE, Graham SJ. The epidemiology of urolithiasis in an ethnically diverse population living in the same area. Urol J 2016;13:2754-8.
5. Mittal A, Tandon S, Singla SK, Tandon C. In vitro inhibition of calcium oxalate crystallization and crystal adherence to renal tubular epithelial cells by Terminalia arjuna. Urolithiasis 2016;44:117-25.
6. Cano R, Carrasco J, Pérula LA, Jiménez C, Olaya I, Criado M, et al. Prevalence of renal stones in Andalusian population: Results of PreLiRenA study. Actas Urol Esp 2015;39:26-31.
7. Nalini HS, Manickavasakam K, Thomas MW. Prevalence and risk factors of kidney stone. GJRA 2016;5:183-7.
8. Sarroca M, Arada A. Litiasis renal. AMF 2015;11:314-23.
9. Alelign T, Petros B. Kidney stone disease: An update on current concepts. Advances in Urology 2018;2018:1-12.
10. Bashir S, Gilani AH. Antiurolithic effect of berberine is mediated through multiple pathways. Eur J Pharmacol 2011;651:168-75.
11. Rodgers AL. Physicochemical mechanism of stone formation. Urolithiasis 2017;45:27-32.
12. Grases F, Genestar C, Conte A. Inhibidores de la litiasis renal: evolución histórica, situación actual y perspectivas futuras. Medicina Clínica 1988;90:83-87.
13. Tsujihata M. Mechanism of calcium oxalate renal stone formation and renal tubular cell injury. Int J Urol 2008;15:115-20.
14. Johri N, Cooper B, Robertson W, Choong S, Rickards D, Unwin R. An update and practical guide to renal stone management. Nephron Clin Pract 2010;116:159-71.
15. Green W, Ratan H. Molecular mechanisms of urolithiasis. Urology 2013;81:701-4.
16. Sethmann I, Nordahl GW, Knoll T, Enzmann F, Simon L, Kleebe HJ. Microstructures of Randall’s plaques and their interfaces with calcium oxalate monohydrate kidney stones reflect underlying mineral precipitation mechanisms. Urolithiasis 2017;45:235-48.
17. Mirian EC, Juanita NM, Christophe BO, Estela MC. Molecular mechanisms involved in the protective effect of the chloroform extract of Selaginella lepidophylla (Hook. et Grev.) Spring in a lithiasic rat model. Urolithiasis 2013;41:205-15.
18. Vaitheeswari S, Sriram R, Brindha P, Kurian GA. Studying inhibition of calcium oxalate stone formation: an in vitro approach for screening hydrogen sulfide and its metabolites. Int Braz J Urol 2015;41:503-10.
19. Grases F, Costa-Bauzá A. Phytate (IP6) is a powerful agent for preventing calcifications in biological fluids: usefulness in renal lithiasis treatment. Anticancer Res 1999;19:3717-22.
20. González G. Litiasis renal: estudio y manejo endocrinológico. Rev Med Clin Condes 2013;24:798-803.
21. Semins MJ, Matlaga BR. Medical evaluation and management of urolithiasis. Ther Adv Urol 2010;2:3-9.
22. Arrabal-Polo MA, Arrabal-Martin M, Garrido-Gomez J. Calcium renal lithiasis: metabolic diagnosis and medical treatment. Sao Paulo Med J 2013;131:46-53.
23. Rathod NR, Biswasa D, Chitmeb HR, Ratna S, Muchandia IS, Chandra R. Anti-urolithiatic effects of Punica granatum in male rats. J Ethnopharmacol 2012;140:234-8.
24. Rodríguez NF, Pérez JA, Iglesias JC, Gallego RM, Veiga BL, Cotelo NV. Actualidad de las plantas medicinales en terapéutica. Acta Farmacéutica Portuguesa 2015;4:42-52.
25. Petrovska BB. Historical review of medicinal plants’ usage. Pharmacogn Rev 2012;6:1-5.
26. Escalona LJ, Tase A, Estrada A, Almaguer ML. Uso tradicional de plantas medicinales por el adulto mayor en la comunidad serrana de Corralillo Arriba. Guisa, Granma. Revista Cubana de Plantas Medicinales 2015;20:429-39.
27. Majouli K, Hamdi A, Hlila MB. Phytochemical analysis and biological activities of Hertia cheirifolia L. roots extracts. Asian Pac J Trop Med 2017;10:1134-9.
28. Calixto JB. Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res 2000;33:179-89.
29. Ahmed S, Mallick IA, Hasan MM. Exploring globally used antiurolithiatic plants of A to L families: Asteraceae, Fabaceae and Lamiaceae revisited. Journal of Pharmacognosy and Phytochemistry 2017;6:1780-7.
30. Ahmed S, Hasan MM. Exploring globally used antiurolithiatic plants of M to R families: Including Myrtaceae, Phyllantaceae, Piperaceae, Polygonaceae, Rubiaceae and Rutaceae. Journal of Pharmacognosy and Phytochemistry 2017;6:325-35.
31. Ahmed S, Hasan MM. Exploring globally used antiurolithiatic plants of M to R families: Including Saxifragaceae, Scrophulariaceae, Solanaceae, Urticaceae, Vitaceae, Zingiberaceae and Zygophyllaceae. Journal of Pharmacognosy and Phytochemistry 2017; 6:325-35.
32. Ahmed S, Giliani SMU, Hasan M. Antiurolithiatic potential of globally used medicinal plants belonging to the family Rosaceae. Journal of Pharmacognosy and Phytochemistry 2017;6:1028-31.
33. Ahmed S, Hasan MM. A review on globally used antiurolithiatic monoherbal formulation belonging to Boraginaceae, Brassicaceae, Malvaceae and Poaceae families. World Journal of Pharmacy and Pharmaceutical Sciences 2017;6:48-61.
34. Callejas S, Loyola O, Díaz H, López F, Rodríguez JA. Historia de Cuba. Pueblo y Educación: La Habana, 2010.p.1-6.
35. Martí J. Diario de Campaña. De Cabo Haitiano a Dos Ríos. Biblioteca Virtual Universal. Editorial del Cardo, 2003. Disponible en: http://www.biblioteca.org.ar
36. Roig JT. Plantas medicinales, aromáticas o venenosas de Cuba. Tomo I, 2da Edición. Cuba: Editorial Ciencia y Técnica, 2012. Págs.: 228-229.
37. Scull R, Miranda M, Infante R. Plantas medicinales de uso tradicional en Pinar del Río. Estudio etnobotánico. I. Rev Cubana Farm 1998;32:57-62.
38. Boffill MA. Plantas Medicinales usadas en Cuba con efecto diurético comprobado experimentalmente. Medicentro 2008;12(1). http://www.revmedicentro.sld.cu/index.php/medicentro/article/view/1183/1535
39. Beyra A, León MC, Iglesias E, Ferrándiz D, Herrera R, Volpato G, et al. Estudios etnobotánicos sobre plantas medicinales en la provincia de Camagüey (Cuba). Anales del Jardín Botánico de Madrid 2004;61:185-203.
40. Godínez D, Volpato G. Plantas medicinales que se venden en el mercado El Río, Camagüey, Cuba. Revista Mexicana de Biodiversidad 2008;79:243-259.
41. Cano JH, Volpato G. Herbal mixtures in the traditional medicine of eastern Cuba. J Ethnopharmacol 2004;90:293-316.
42. Volpato G, Godínez D, Beyra A, Barreto A. Uses of medicinal plants by Haitian immigrants and their descendants in the Province of Camaüey, Cuba. J Ethnobiol Ethnomed 2009;5:16.
43. Riverón FB, Hernández Y, García A, Escalona RY. La colección de plantas medicinales del Jardín Botánico de Holguín, Cuba: su importancia social y científica. Revista del Jardín Botánico Nacional 2015;36:219-22.
44. Bashir S, Gilani AH. Antiurolithic effect of Bergenia ligulata rhizome: an explanation of the underlying mechanisms. J Ethnopharmacol 2009;122:106-16.
45. Pérez RA, Rivas C, Ramos ML. Actividad antiurolítica. En: Rivas C, Oranday MA, Verde MJ, editors. Investigación en plantas de importancia médica. México: Omnia Science; 2016.p.161-70.
46. Pérez RA; Leos C; Oranday MA, Hernández CE, Sánchez E; Rivas C. Efecto in vitro en la inhibición del proceso de nucleación en litiasis renal, capacidad de captura de radicales libres, actividad antimicrobiana y tóxica del extracto metanólico de Berberis trifoliata. Revista Mexicana de Ciencias Farmacéuticas 2015;46:70-76.
47. Ahmed S, Hasan MM, Khan H, Mahmood ZA, Patel S. The mechanistic insight of polyphenols in calcium oxalate urolithiasis mitigation. Biomed Pharmacother 2018;106:1292-9.
48. Zeng X, Xi Y, Jiang W. Protective role of flavonoids and flavonoid-rich plant extracts against urolithiasis: A review. Food Sciences and Nutrition 2018. Available at: http://doi.org/10.1080/10408398.2018.1439880
49. Newman DJ, Cragg GM. Natural Products as Sources of New Drugs from 1981 to 2014. J Nat Prod 2016;79:629-61.
50. Butterweck V, Khan SR. Herbal Medicines in the Management of Urolithiasis: Alternative or Complementary? Planta Med 2009;75:1095-103.
Downloads
Published
22-01-2020
How to Cite
González, A. F., Pieters, L., & Hernández, R. D. (2020). Effectiveness of Herbal Medicine in Renal Lithiasis: a Review. Siriraj Medical Journal, 72(2), 188–194. https://doi.org/10.33192/Smj.2020.25
Issue
Section
Review Article
License
Authors who publish with this journal agree to the following conditions:
Copyright Transfer
In submitting a manuscript, the authors acknowledge that the work will become the copyrighted property of Siriraj Medical Journal upon publication.
License
Articles are licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). This license allows for the sharing of the work for non-commercial purposes with proper attribution to the authors and the journal. However, it does not permit modifications or the creation of derivative works.
Sharing and Access
Authors are encouraged to share their article on their personal or institutional websites and through other non-commercial platforms. Doing so can increase readership and citations.
