Ovarian Cancer in Pregnancy at Siriraj Hospital: A Thirteen-Year Review (1998-2010)

Authors

  • Chairat Leelaphattanadit Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Saifon Chawanpaiboon Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Siripong Sawasdimongkol Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700

Keywords:

Ovarian cancer; pregnancy

Abstract

Objective: To determine the prevalence of ovarian cancer, staging, presenting symptoms, gestational age of diagnoses, screening and diagnostic methods and pregnancy outcomes during pregnancy at Siriraj Hospital over a 13-year period (1998-2010).
Methods: Medical records of pregnant women diagnosed with ovarian cancer at Siriraj Hospital from 1998 to 2010 were reviewed. Results: During the 13-year period, 1998-2010, eight cases of pregnant women with ovarian cancer were detected. Six cases of ovarian cancer stage I and 2 cases of ovarian cancer stage II were recorded. All of the patients presented with the symptom of abdominal mass. Two cases presented with abdominal pain. Ultrasonography was performed in all cases to confirm the diagnosis. Two patients with stage II ovarian cancer which was diagnosed in early pregnancy, subsequently had abortions. Five cases from 6 cases of those patients with stage I ovarian cancer underwent caesarean delivery while one case had a normal vaginal delivery.
Conclusion: Regarding to this 13-year review, the prevalence of ovarian cancer in pregnancy was low. The management of pregnant patients with ovarian cancer depended on the gestational age and the staging of malignancy.

References

1. www.cancer.gov/cancertopics/factsheet/risk/brca (accessed January 29,2009).
2. Leiserowitz GS, Xing G, Cress R, Brahmbhatt B, Dalrymple JL, Smith LH. Adnexal masses in pregnancy: how often are they malignant? Gynecol
Oncol. 2006 May;101(2):315-21.
3. Leiserowitz GS, Xing G, Cress R, Brahmbhatt B, Dalrymple JL, Smith LH. Adnexal masses in pregnancy: how often are they malignant? Gynecol
Oncol. 2006 May;101(2):315-21.
4. Goff BA, Mandel LS, Drescher CW, Urban N, Gough S, Schurman KM, et al. Development of an ovarian cancer symptom index: possibilities for
earlier detection. Cancer. 2007 Jan 15;109(2):221-7.
5. Yen CF, Lin SL, Murk W, Wang CJ, Lee CL, Soong YK, et al. Risk analysis of torsion and malignancy for adnexal masses during pregnancy.
Fertil Steril. 2009 May;91(5):1895-902.
6. Telischak NA, Yeh BM, Joe BN, Westphalen AC, Poder L, Coakley FV. MRI of adnexal masses in pregnancy. AJR Am J Roentgenol. 2008 Aug;191(2):364-70.
7. ACOG Committee on Obstetric Practice. ACOG Committee Opinion. Number 299, September 2004 (replaces No. 158, September 1995). Guidelines
for diagnostic imaging during pregnancy. Obstet Gynecol. 2004 Sep;104(3):647-51.
8. Giuntoli RL, 2nd, Vang RS, Bristow RE. Evaluation and management of adnexal masses during pregnancy. Clin Obstet Gynecol. 2006 Sep;49(3):
492-505.
9. Schmeler, KM, Mayo-Smith WW, Peipert, JF, Weitzen S, Manuel MD, Gordinier ME. Adnexal masses in pregnancy: surgery compared with observation. Obstet Gynecol. 2005 May;105(5 Pt 1):1098-103.
10. Sarandakou A, Protonotariou E, Rizos D. Tumor markers in biological fluids associated with pregnancy. Crit Rev Clin Lab Sci. 2007;44(2):151-78.
11. Mooney J, Silva E, Tornos C, Gershenson D. Unusual features of serous neoplasms of low malignant potential during pregnancy. Gynecol Oncol. 1997 Apr;65(1):30-5.
12. Bakri YN, Ezzat A, Akhtar, Dohami, Zahrani. Malignant germ cell tumors of the ovary. Pregnancy considerations. Eur J Obstet Gynecol Reprod Biol. 2000 May;90(1):87-91.
13. Leiserowitz GS. Managing ovarian masses during pregnancy. Obstet Gynecol Surv. 2006 Jul;61(7):463-70.
14. Lee GS, Hur SY, Shin JC, Kim SP, Kim SJ. Elective vs. conservative management of ovarian tumors in pregnancy. Int J Gynaecol Obstet. 2004 Jun;85(3):250-4.
15. Leiserowitz GS. Managing ovarian masses during pregnancy. Obstet Gynecol Surv. 2006 Jul;61(7):463-70.

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Published

03-04-2020

How to Cite

Leelaphattanadit, C. ., Chawanpaiboon, S. ., & Sawasdimongkol, S. . (2020). Ovarian Cancer in Pregnancy at Siriraj Hospital: A Thirteen-Year Review (1998-2010). Siriraj Medical Journal, 63(2), 38–41. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/240904

Issue

Vol. 63 No. 2 (2011): March-April

Section

Original Article

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