A Pilot Comparison Study of Setup Verif ication Between Two-Dimensional Kilo-Voltage (2DkV) Matchand Kilo-Voltage Cone-Beam Computed Tomography (kV-CBCT) Match for Nasopharyngeal Cancer Patients

Authors

  • Kullathorn Thephamongkhol Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Kanyanee Laebua Radiation Oncology Unit, Chulabhorn Hospital, Bangkok
  • Pittaya Dankulchai Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 107
  • Janjira Petsuksiri Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Chumpot Kakanaporn Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Lalida Tuntipumiamorn Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Porntip Iampongpaiboon Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Yaowalak Chansilpa Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Pittayapoom Pattaranutraporn Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700

Keywords:

2DkV match; CBCT match; nasopharyngeal carcinoma; IMRT

Abstract

Objective: Setup verification is the critical part to make sure of the accuracy for Intensity-modulated radiotherapy in nasopharyngeal cancer patients. This pilot study was designed to answer whether and how much the kV-CBCT in addition to 2DkV is more accurate than 2DkV alone in terms of verification parameters.
Methods: Images acquisition: Offline images were displayed in the matched position between reference images. 2D and 3D matches: The bony matches were done by using the location of the tumor in the nasopharyngeal and upper neck regions. The distances displaced from the isocenter were recorded in x-y-z directions. Analysis: The distance of the isocenter shift in each direction (X, Y, Z) were presented as point estimations. The alignment between the two methods was assessed with Pearson’s and Spearman’s correlation. The 3 mm difference within 90% is considered as an acceptable range of non-inferiority of 2DkV, compared with CBCT.
Results: 11 nasopharyngeal cancer patients were included into this study. The correlation between 2DkV and kV-CBCT were 0.46, 0.11 and 0.16 for Superior-inferior (SI), Anterior-posterior (AP) and Left-right (LR) directions, respectively. The central value for the kV-CBCT; SI, AP and LR directional shift were 0.07, 0.06 and 0.03 cm, respectively, whereas the central value
for 2DkV; SI, AP and LR directional shift were 0.05, 0.07 and 0.04 cm. For the difference shift < 3 mm, the results > 90% were within acceptable value: 100% and 96.96% for SI and LR directions whereas the AP direction was 87.87%.
Conclusion: Compared with kV-CBCT by using our criteria, 2DkV images are accurate enough for treatment verification in nasopharyngeal cancer patients.

References

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Published

03-04-2020

How to Cite

Thephamongkhol, K. ., Laebua, K. ., Dankulchai, P. ., Petsuksiri, J. ., Kakanaporn, C. ., Tuntipumiamorn, L. ., Iampongpaiboon, P. ., Chansilpa, Y. ., & Pattaranutraporn, P. . (2020). A Pilot Comparison Study of Setup Verif ication Between Two-Dimensional Kilo-Voltage (2DkV) Matchand Kilo-Voltage Cone-Beam Computed Tomography (kV-CBCT) Match for Nasopharyngeal Cancer Patients. Siriraj Medical Journal, 63(2), 47–51. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/240906

Issue

Vol. 63 No. 2 (2011): March-April

Section

Original Article

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