Thyroid Cancer Presenting as an Incidentaloma Detected on F-18 FDG PET/CT Imaging: A Case Report
Keywords:
PET/CT; incidentaloma; thyroid cancerAbstract
The authors report a woman with a history of malignant B-cell lymphoma (MALT lymphoma) at the lower lobe of
the left lung status post left lower lobe lobectomy who underwent F-18 FDG PET/CT whole-body imaging for evaluation of
any suspicious new pulmonary lesion. The study incidentally found abnormal focal hypermetabolic activity, called incidentaloma,
at the right thyroid lobe, which was pathologically proven to be papillary thyroid carcinoma. She was further treated
with radioiodine therapy after a total thyroidectomy had been done.
References
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incidental findings detected on FDG-PET scintigraphy. Semin Nucl Med.
2010 Jul;40(4):294-315.
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Nathan MA, et al. Clinical significance of diffusely increased 18F-FDG
uptake in the thyroid gland. J Nucl Med. 2007 Jun;48(6):896-901.
6. Liu Y. Clinical significance of thyroid uptake on F 18-fluorodeoxyglucose
positron emission tomography. Ann Nucl Med. 2009 Jan;23(1):17-23.
7. Chen YK, Chen YL, Cheng RH, Yeh CL, Lee CC, Hsu CH. The significance
of FDG uptake in bilateral thyroid glands. Nucl Med Commun.
2007 Feb;28(2):117-22.
8. Burguera B, Gharib H. Thyroid incidentalomas. Prevalence, diagnosis,
significance, and management. Endocrinol Metab Clin North Am. 2000
Mar;29(1):187-203.
9. Shie P, Cardarelli R, Sprawls K, Fulda KG, Taur A. Systematic review:
prevalence of malignant incidental thyroid nodules identified on fluorine-18
fluorodeoxyglucose positron emission tomography. Nucl Med Commun.
2009 Sep;30(9):742-8.
10. Bogsrud TV, Karantanis D, Nathan MA, Mullan BP, Wiseman GA, Collins
DA, et al. The value of quantifying 18F-FDG uptake in thyroid nodules
found incidentally on whole-body PET-CT. Nucl Med Commun. 2007
May;28(5):373-81.
11. Are C, Hsu JF, Schoder H, Shah JP, Larson SM, Shaha AR. FDG-PET
detected thyroid incidentalomas: need for further investigation? Ann Surg
Oncol. 2007 Jan;14(1):239-47.
12. Choi JY, Lee KS, Kim HJ, Shim YM, Kwon OJ, Park K, et al. Focal
thyroid lesions incidentally identified by integrated 18F-FDG PET/CT:
Clinical significance and improved characterization. J Nucl Med. 2006
Apr;47(4):609-15.
GH, et al. Recommendations on the use of F18-FDG PET in oncology.
J Nucl Med. 2008 Mar;49(3):480-508.
2. Poeppel TD, Krause BJ, Heusner TA, Boy C, Bockisch A, Antoch G.
PET/CT for the staging and follow-up of patients with malignancies. Eur
J Radiol. 2009 Jun;70(3):382-92.
3. Ishimori T, Patel PV, Wahl RL. Detection of unexpected additional primary
malignancies with PET/CT. J Nucl Med. 2005 May;46(5):752-7.
4. Liu Y, Ghesani NV, Zuckier LS. Physiology and pathophysiology of
incidental findings detected on FDG-PET scintigraphy. Semin Nucl Med.
2010 Jul;40(4):294-315.
5. Karantanis D, Bogsrud TV, Wiseman GA, Mullan BP, Subramaniam RM,
Nathan MA, et al. Clinical significance of diffusely increased 18F-FDG
uptake in the thyroid gland. J Nucl Med. 2007 Jun;48(6):896-901.
6. Liu Y. Clinical significance of thyroid uptake on F 18-fluorodeoxyglucose
positron emission tomography. Ann Nucl Med. 2009 Jan;23(1):17-23.
7. Chen YK, Chen YL, Cheng RH, Yeh CL, Lee CC, Hsu CH. The significance
of FDG uptake in bilateral thyroid glands. Nucl Med Commun.
2007 Feb;28(2):117-22.
8. Burguera B, Gharib H. Thyroid incidentalomas. Prevalence, diagnosis,
significance, and management. Endocrinol Metab Clin North Am. 2000
Mar;29(1):187-203.
9. Shie P, Cardarelli R, Sprawls K, Fulda KG, Taur A. Systematic review:
prevalence of malignant incidental thyroid nodules identified on fluorine-18
fluorodeoxyglucose positron emission tomography. Nucl Med Commun.
2009 Sep;30(9):742-8.
10. Bogsrud TV, Karantanis D, Nathan MA, Mullan BP, Wiseman GA, Collins
DA, et al. The value of quantifying 18F-FDG uptake in thyroid nodules
found incidentally on whole-body PET-CT. Nucl Med Commun. 2007
May;28(5):373-81.
11. Are C, Hsu JF, Schoder H, Shah JP, Larson SM, Shaha AR. FDG-PET
detected thyroid incidentalomas: need for further investigation? Ann Surg
Oncol. 2007 Jan;14(1):239-47.
12. Choi JY, Lee KS, Kim HJ, Shim YM, Kwon OJ, Park K, et al. Focal
thyroid lesions incidentally identified by integrated 18F-FDG PET/CT:
Clinical significance and improved characterization. J Nucl Med. 2006
Apr;47(4):609-15.
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Published
03-04-2020
How to Cite
Sriprapaporn, J. ., Srisuwan, B. ., Uiprasertkul, M. ., Tuchinda, P. ., Thongpraparn, T. ., & Hannanthawiwat, C. . (2020). Thyroid Cancer Presenting as an Incidentaloma Detected on F-18 FDG PET/CT Imaging: A Case Report. Siriraj Medical Journal, 63(6), 207–209. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/241538
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