Retracted: The Increasing Risk of Dementia in Psoriasis: A Systematic Review and Meta-Analysis

Authors

  • Chayada Chaiyabutr Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand http://orcid.org/0000-0002-3161-5206
  • Narumol Silpa-archa Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand http://orcid.org/0000-0002-1678-5442
  • Chanisada Wongpraparut Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand http://orcid.org/0000-0002-9014-3229
  • Leena Chularojanamontri

DOI:

https://doi.org/10.33192/Smj.2021.19

Keywords:

Psoriasis, dementia, cognitive impairment, Alzheimer’s disease, comorbidities

Abstract

Objective: To systemically summarize and meta-analyze the risk of dementia in psoriasis patients.

Methods: A systematic review was performed in two databases (EMBASE and MEDLINE). The eligible studies had to be a cohort study or a cross-sectional study that compared either the prevalence or incidence of dementia in patients with psoriasis, versus individuals without psoriasis.

Results: Of 791 retrieved articles, seven studies met the inclusion criteria and were included into the meta-analysis. The risk of incident and prevalent dementia were significantly higher in patients with psoriasis, with a pooled risk ratio of 1.16 (95% CI: 1.02-1.33; I2 96%) and 1.36 (95% CI: 1.07-1.72; I2 10%), respectively.

Conclusions: This study revealed a slight increase in both the incidence and prevalence of dementia in psoriasis patients. However, dermatologists should carefully observe and periodically screen psoriasis patients for this comorbidity, especially among those who have symptoms and signs of cognitive impairment.

 

This article was retracted on 10 May 2021

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Published

17-02-2021

How to Cite

Chaiyabutr, C., Silpa-archa, N. ., Wongpraparut, C. ., & Chularojanamontri, L. (2021). Retracted: The Increasing Risk of Dementia in Psoriasis: A Systematic Review and Meta-Analysis. Siriraj Medical Journal, 73(3), 145–154. https://doi.org/10.33192/Smj.2021.19

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Original Article