Retrospective Review of The Relationship Between Parity and Pregnancy Outcomes at Siriraj Hospital

Abstract

Objective: To determine the effect of parity to pregnancy outcomes.

Methods: A retrospective study was conducted among 976 singleton pregnant women during July to October 2007 at Siriraj Hospital. Two groups of patients were recruited in this study, the first group was nulliparity (488 patients) and the second group was multiparity (488 patients). The adverse pregnancy outcomes including antepartum hemorrhage (APH), gestational diabetes (GDM), pre-eclampsia, preterm birth, premature rupture of membranes (PROM), mode of delivery, postpartum hemorrhage (PPH) and neonatal morbidity were studied comparatively.

Results: The adverse pregnancy outcome in the aspects of pre-eclampsia, PROM, preterm birth, operative obstetrics and neonatal phototherapy in nulliparity were significantly higher than multiparity with odds ratio 2.43 (95%CI 1.05-5.61), 1.79 (95%CI 1.07-2.98), 1.91 (95%CI 1.23-2.96), 11.20 (95%CI 2.60-48.13), and 2.10 (95%CI 1.40-3.14) respectively. APH was increased in the multiparity group but not significant different by statistics, with odds ratio 5.04 (95%CI 0.59-43.31). There were no significant differences for the prevalence of GDM, PPH, low birth weight and macrosomia in these two groups.

Conclusion: Increased risk of pre-eclampsia, PROM, preterm birth, operative obstetrics and neonatal phototherapy in nulliparity compared with multiparity.