Primary Systemic Amyloidosis

Abstract

Amyloidosis AL is a disease which is caused by abnormal production of protein and accumulation at body organs. It causes pathological change and alters organ function especially in vital organs that can initiate fatal complications. The causes are idiopathic or acquired from multiple myeloma. Early diagnosis and prompt immediate treatment is the best way to prevent vital organ involvement. However, the clinical manifestations are heterogenous and not specific which means the diagnosis is not met at the first visit. Consideration of its conditions is basically to find out early signs of the disease. The treatments are based on the performance status of patients and impairment of some organs and aims to provide suitable care such as chemotherapy, immune suppressive drugs or transplantation of stem cells.