Reference Values of Serum Anti-streptolysin O in Adults by Nephelometry

Authors

  • Ronnachai Viriyataveekul Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Supaporn Chaihirunkarn Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Sumalee Potprasat Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Sudarat Sarovath Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Sasitorn Bejrachandra Department of Transfution Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700

Keywords:

Reference Values, Serum, Anti-streptolysin O, Nephelometry

Abstract

The anti-streptolysin O (ASO) test, which depends upon age and geographic location, is used to provide evidence for antecedent streptococcal infection in patients suspected of having rheumatic fever. Reference values of ASO have not previously been determined by nephelometric assay for laboratory use at Siriraj Hospital. A total of 402 serum specimens were collected from healthy adults aged between 16 and 63 years in Siriraj Hospital. They consisted of 235 blood donors, 150 subjects who were going to study aboard and 17 dentists. ASO concentrations from 5 groups according to five age ranges were compared and it was found that two age ranges which were 25 years old and younger and 26 years and older were appropriate to determine reference values. The reference values of ASO for these two age ranges, with 90% confidence intervals, were 486 (401-673) IU/ml and 385 (362-500) IU/ml, respectively.

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Published

24-08-2020

How to Cite

Viriyataveekul, R. ., Chaihirunkarn, S. ., Potprasat, S. ., Sarovath, S. ., & Bejrachandra, S. . (2020). Reference Values of Serum Anti-streptolysin O in Adults by Nephelometry. Siriraj Medical Journal, 53(8), 530–533. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/244996

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Original Article