Discordant Cardiac Troponin Results in Amphetamine - Related Rhabdomyolysis

Authors

  • Kosit Sribhen Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

-

Abstract

A case of a patient who developed amphetamine-related rhabdomyolysis and acute renal failure after an intestinal operation is reported. He initially had biochemical evidence of myocardial injury, with a concomitant increase in cardiac marker proteins CK-MB, cardiac troponin T (cTnT) and cardiac troponin I (cTnI) during the acute event. Following intensive treatment and improvement in renal function, levels of all myocardial marker proteins fell towards the normal range. Late in the course of the disease, however, there were re-elevations of CK-MB and cTnT, but not of cTnI, to levels exceeding 14 fold and 8 fold the upper limit of the reference range, respectively. Since, at present the possibility of re-expression of both CK-MB and cTnT in damaged and regenerating skeletal muscle can not be ruled out, the late occurrence of increased CK-MB and cTnT in our patient should not be interpreted as evidence of recurrent myocardial injury.

Downloads

Published

01-03-2002

How to Cite

Sribhen, K. (2002). Discordant Cardiac Troponin Results in Amphetamine - Related Rhabdomyolysis. Siriraj Medical Journal, 54(3), 181–187. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245011

Issue

Vol. 54 No. 3 (2002): March

Section

Interdepartment Conference

License

Users are free to share, copy, and redistribute all articles published in the Siriraj Medical Journal (SMJ) in any medium or format as long as you follow the following terms:

  • Attribution — You must give appropriate credit, provide a link to the material, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the publisher endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.