Chronic Granulomatous Disease with Disseminated Trichosporonosis : A Case Report

Authors

  • Samonmars Kanngurn Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Paisal Parichatikanond Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Visanu Pootong Department of Pediatic, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Pakit Vichyanond Department of Pediatric, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700

Keywords:

Chronic Granulomatous Disease, Disseminated Trichosporonosis

Abstract

A case of a two year and three month old Thai boy with a history of recurrent bacterial infections since aged 2 months. A definite absence of superoxide activity in the patient' s granulocytes detected by nitroblue tetrazolium test indicated the diagnosis of chronic granulomatous disease. He suffered from septicemia and systemic fungal infection, resulting in death despite rigorous medical care. The postmortem findings showed extensive granulomatous inflammation in several internal organs. Tissue culture led to diagnosis of disseminated trichosporonosis, an uncommon infection in immunocompromised patients. This is the first case report of disseminated trichosporonosis in a chronic granulomatous disease patient.

Downloads

Published

27-08-2020

How to Cite

Kanngurn, S. ., Parichatikanond, P. ., Pootong, V. ., & Vichyanond, P. . (2020). Chronic Granulomatous Disease with Disseminated Trichosporonosis : A Case Report. Siriraj Medical Journal, 53(8), 542–548. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245021

Issue

Vol. 53 No. 8 (2001): August

Section

Case Report

License

Authors who publish with this journal agree to the following conditions:

Copyright Transfer

In submitting a manuscript, the authors acknowledge that the work will become the copyrighted property of Siriraj Medical Journal upon publication.

License

 Articles are licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). This license allows for the sharing of the work for non-commercial purposes with proper attribution to the authors and the journal. However, it does not permit modifications or the creation of derivative works.

Sharing and Access

Authors are encouraged to share their article on their personal or institutional websites and through other non-commercial platforms. Doing so can increase readership and citations.