Chronic Granulomatous Disease with Disseminated Trichosporonosis : A Case Report

Authors

  • Samonmars Kanngurn Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Paisal Parichatikanond Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Visanu Pootong Department of Pediatic, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700
  • Pakit Vichyanond Department of Pediatric, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700

Keywords:

Chronic Granulomatous Disease, Disseminated Trichosporonosis

Abstract

A case of a two year and three month old Thai boy with a history of recurrent bacterial infections since aged 2 months. A definite absence of superoxide activity in the patient' s granulocytes detected by nitroblue tetrazolium test indicated the diagnosis of chronic granulomatous disease. He suffered from septicemia and systemic fungal infection, resulting in death despite rigorous medical care. The postmortem findings showed extensive granulomatous inflammation in several internal organs. Tissue culture led to diagnosis of disseminated trichosporonosis, an uncommon infection in immunocompromised patients. This is the first case report of disseminated trichosporonosis in a chronic granulomatous disease patient.

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Published

27-08-2020

How to Cite

Kanngurn, S. ., Parichatikanond, P. ., Pootong, V. ., & Vichyanond, P. . (2020). Chronic Granulomatous Disease with Disseminated Trichosporonosis : A Case Report. Siriraj Medical Journal, 53(8), 542–548. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245021

Issue

Section

Case Report