Drug-Induced Stevens-Johnson Syndrome

Authors

  • Adisak Wongkajornsilp Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Kanokvalai Kulthanan Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Panida Kosrirukvongs Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Ajchara Koolvisoot Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Methavee Cheepsomsong Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Thitirat Rattanasila Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Thanatsuda Ua-Boonkul Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Stevens-Johnson syndrome, adverse drug reaction

Abstract

A patient with arthritis receiving allopurinol for 4 weeks developed Stevens-Johnson syndrome (SJS). SJS is a potentially life-threatening adverse drug reaction and is most commonly associated with the sulfa antibiotics, allopurinol, NSAIDs, and anticonvulsants. The skin reaction spread symmetrically over the body and involved the conjunctiva. The diagnosis and different models of treatment for this case are discussed. Alternative treatments for gouty arthritis are presented. Strategic planning for novel research opportunities arising from this disease is outlined.

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Published

01-11-2002

How to Cite

Wongkajornsilp, A. ., Kulthanan, K. ., Kosrirukvongs, P. ., Koolvisoot, . A., Cheepsomsong, M., Rattanasila, T. ., & Ua-Boonkul, T. . (2002). Drug-Induced Stevens-Johnson Syndrome. Siriraj Medical Journal, 54(11), 721–728. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245330

Issue

Vol. 54 No. 11 (2002): November

Section

Interdepartment Conference

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