Drug-Induced Stevens-Johnson Syndrome

Authors

  • Adisak Wongkajornsilp Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Kanokvalai Kulthanan Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Panida Kosrirukvongs Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Ajchara Koolvisoot Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Methavee Cheepsomsong Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Thitirat Rattanasila Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Thanatsuda Ua-Boonkul Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Stevens-Johnson syndrome, adverse drug reaction

Abstract

A patient with arthritis receiving allopurinol for 4 weeks developed Stevens-Johnson syndrome (SJS). SJS is a potentially life-threatening adverse drug reaction and is most commonly associated with the sulfa antibiotics, allopurinol, NSAIDs, and anticonvulsants. The skin reaction spread symmetrically over the body and involved the conjunctiva. The diagnosis and different models of treatment for this case are discussed. Alternative treatments for gouty arthritis are presented. Strategic planning for novel research opportunities arising from this disease is outlined.

Downloads

Published

01-11-2002

How to Cite

Wongkajornsilp, A. ., Kulthanan, K. ., Kosrirukvongs, P. ., Koolvisoot, . A., Cheepsomsong, M., Rattanasila, T. ., & Ua-Boonkul, T. . (2002). Drug-Induced Stevens-Johnson Syndrome. Siriraj Medical Journal, 54(11), 721–728. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245330

Issue

Vol. 54 No. 11 (2002): November

Section

Interdepartment Conference

License

Authors who publish with this journal agree to the following conditions:

Copyright Transfer

In submitting a manuscript, the authors acknowledge that the work will become the copyrighted property of Siriraj Medical Journal upon publication.

License

 Articles are licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). This license allows for the sharing of the work for non-commercial purposes with proper attribution to the authors and the journal. However, it does not permit modifications or the creation of derivative works.

Sharing and Access

Authors are encouraged to share their article on their personal or institutional websites and through other non-commercial platforms. Doing so can increase readership and citations.