Amikacin: Area Under Curve for Once Daily Dose and Its Correlation with Plasma Concentration at Six Hours Post Infusion

Main Article Content

Teera Kolladaruengkri
Kamol Udol
Kantima Sangsiriwut
Dujpratana Pisalsarakij
Surapol Suwanagool

Abstract

Aminoglycosides are commonly used for gram-negative septicemia. Formerly, peak and trough plasma levels were the monitoring parameters for conventional dose which was every eight hours. At present the recommended dose is once daily and the recommended monitoring parameters are the area under concentration time curve and the six-hour (range 146-180) for the area under curve and 6.79 milligrams per liter (range 5.6-7.9) for the six-hour plasma concentration post-infusion. The correlation of the area under curve and the six-hour plasma concentration post-infusion was reported in a linear equation with significance.

Downloads

Download data is not yet available.

Article Details

How to Cite
Kolladaruengkri, T. ., Udol, K. ., Sangsiriwut, K. ., Pisalsarakij, D. ., & Suwanagool, S. . (2003). Amikacin: Area Under Curve for Once Daily Dose and Its Correlation with Plasma Concentration at Six Hours Post Infusion. Siriraj Medical Journal, 55(3), 133–138. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245387
Section
Original Article