Effect of Pentoxifylline on Human Sperm Preparation
Keywords:
Pentoxifylline, Human SpermAbstract
The aim of the research was to study the effects of pentoxifylline on the sperm motility. Thirty samples of semen were studied. Each sample was divided into two sub-samples swim up technique. The other sub-samples were mixed with 3.3 mmol pentoxifylline solution for thirty minutes before entering the process of the sperm swim up preparation. The data regarding sperm concentration, motility, and morphology after 5 minutes of the swim up were recorded. The study showed that the samples that were mixed with 3.3 mmol pentoxifylline had a significantly higher sperm concentration (p< 0.001), greater sperm motility (p = 0.014), and a more normal sperm morphology (p < 0.001) than those samples prepared using the conventional method. It was concluded that pentoxifylline added in the process of sperm preparation could improve the sperm quality outcome.
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