Serotonin Syndrome with Rhabdomyolysis: A Case Report and Recommended Prevention

Authors

  • Weerasak Muangpaisan Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Songchai Chinwattanakul Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Naruemon Dhana Department of Pharmacy, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Supachoke Singhakant Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Serotonin syndrome, Neuroleptic malignant syndrome;, Rhabdomyolysis

Abstract

Serotonin syndrome is a severe but preventable adverse drug reaction. This syndrome is rare and usually underrecognized. It is resulted from the excessive serotonin receptor stimulation, mostly by combination of serotonergic agents. The clinical triads are altered mental status, autonomic dysfunction and neuromuscular abnormalities. Occasionally, severe cases of serotonin syndrome are complicated by rhabdomyolysis and other potentially life-threatening conditions. In this report, we describe a 22-year-old man presenting with serotonin syndrome and rhabdomyolysis from serotonergic drug interaction. In addition, recommendation of preventive strategies is included.

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Published

01-08-2005

How to Cite

Muangpaisan, W. ., Chinwattanakul, S. ., Dhana, N. ., & Singhakant, S. . (2005). Serotonin Syndrome with Rhabdomyolysis: A Case Report and Recommended Prevention. Siriraj Medical Journal, 57(8), 336–338. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245608

Issue

Vol. 57 No. 8 (2005): August

Section

Case Report

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