Antiprolifrative Activities of Three Thai Medicinal Plants on Human Cancer Cells

Authors

  • Tanawan Kummalue Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Pornchai O-charoenrat Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Weena Jiratchariyakul Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University
  • Monraudee Chanchai Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University
  • Surat Iemsri Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Antiproliferative activities, Pouzolzia pentandra Benn, Erycibe elliptilimba Merr, Gelonium multiflorum A. Juss.

Abstract

In Thailand, the stems and leaves of Pouzolzia pentandra Benn., stems of Erycibe elliptilimba Merr.& Chun., and Gelonium multiflorum A. Juss. have long been used as traditional medicines for cancer therapy. The ethanol, water, methanol:water and ethyl acetate extracts of these three plants were tested in vitro against four different human breast cancer cell lines and two human lung cancer cell lines using MTT screening method. The methanol extract of Erycibe elliptilimba Merr. & Chun. showed the most potent antiproliferative activities against these specific human cancer cells. The results, therefore, suggested to some extent the benefit of the traditional use of Erycibe elliptilimba Merr.& Chun. in the treatment of malignancies.

Downloads

Published

01-11-2005

How to Cite

Kummalue, T. ., O-charoenrat, P. ., Jiratchariyakul, W. ., Chanchai, M. ., & Iemsri, S. . (2005). Antiprolifrative Activities of Three Thai Medicinal Plants on Human Cancer Cells. Siriraj Medical Journal, 57(11), 491–495. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245630

Issue

Vol. 57 No. 11 (2005): November

Section

Original Article

License

Users are free to share, copy, and redistribute all articles published in the Siriraj Medical Journal (SMJ) in any medium or format as long as you follow the following terms:

  • Attribution — You must give appropriate credit, provide a link to the material, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the publisher endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.