Epidemiology of Acinetobacter baumannii Infections in Siriraj Hospital 2002

Main Article Content

Anuwat Keerasuntonpong


Objective: To determine the epidemiology of A.baumannii infections in Siriraj Hospital in 2002.
Methods: From January to December 2002, we prospectively studied hospitalized patients in Siriraj Hospital who had A.baumannii isolated from their clinical specimens.
Results: During the study period, A.baumannii was isolated from clinical specimens of 208 cases. Eighty-six patients (41.3%) had A.baumannii infections whereas 122 patients (58.7%) had A.baumannii colonization. Of the 86 patients with A.baumannii infections, 54.7% were males and 45.3% were females. The mean age of patients was 56.1 years. Ninety-eight percent of the infections were hospital-acquired. The patients developed infection after an average of 26 days of hospitalization. Fifty-two percent of the patients were in the general wards, whereas 48% of them were in ICU. The common sites of infection were respiratory tract and skin and soft tissues. Factors associated with A.baumannii infection were identified in 98.8% of the patients. The most common factors were prior use of antibiotics especially ceftazidime and indwelling medical devices. The susceptibility of A.baumannii to carbapenems, aminoglycosides, beta-lactam/ beta-lactamase inhibitors, co-trimoxazole, fluoroquinolone, 4th generation cephalosporins and 3rd generation cephalosporins was 32%, 16%, 12 %, 9%, 7%, 4% and 3%, respectively. Fiftyseven percent of A.baumannii isolates were resistant to all antimicrobials currently available in Thailand. The overall mortality rate of the patients infected with A.baumannii was 54.7%.
Conclusion: Most A.baumannii infections in Siriraj were hospital-acquired. The most common site of infection was the respiratory tract. The majority of A.baumannii isolates was multi-drug resistant. The mortality rate of A.baumannii infections was high.


Download data is not yet available.

Article Details

How to Cite
Keerasuntonpong, A. (2007). Epidemiology of Acinetobacter baumannii Infections in Siriraj Hospital 2002. Siriraj Medical Journal, 58(8), 951–954. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245860
Original Article