Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia

Authors

  • Sunanta Jindarat U-thong Hospital
  • Chaweewan Muangnoi U-thong Hospital
  • Dalicha Changsiriporn U-thong Hospital
  • Anuchit Platong U-thong Hospital
  • Bangon Thanamontra U-thong Hospital
  • Duangrat Chiewchanwit U-thong Hospital
  • Viparat Vongvanvatana Bangkrathum Hospital
  • Noppawan Rongrungsri Bangkrathum Hospital
  • Kumrai Krittasilp Bangkrathum Hospital
  • Nutteera Kaewkong Bangkrathum Hospital
  • Sairung Kantawan Bangkrathum Hospital
  • Nilnetr Virasombat Soongneon Hospital
  • Veena Mongkolporn Soongneon Hospital
  • Wilai Prakobkij Soongneon Hospital
  • Khanidtha Wanleepong Soongneon Hospital
  • Chatchawal Maneekul Soongneon Hospital
  • Sittikom Benchakhanta The Crown Prince Hospital of Loengnoktha
  • Piyamit Boonpok The Crown Prince Hospital of Loengnoktha
  • Wilaiwan Kunnasut The Crown Prince Hospital of Loengnoktha
  • Laddawan Tongkleaw The Crown Prince Hospital of Loengnoktha
  • Adisorn Vatthanasak Kudchum Hospital
  • Jiranya Mookkhan Kudchum Hospital
  • Chaiwat Jatuporn Wangchan Hospital
  • Kullana Tuntiprawan Wangchan Hospital
  • Sirirung Teerawongseree Wangchan Hospital
  • Saowakhon Ussawasrisuwan Wangchan Hospital
  • Pojawan Thamcharoen Wangchan Hospital
  • Thunyaporn Keawsontaya Wangchan Hospital
  • Anchalee Chuthaputti Department for Development of Thai Traditional and Alternative Medicine, Ministry of Public Health
  • Porntip Termviset Department for Development of Thai Traditional and Alternative Medicine, Ministry of Public Health
  • Visanu Thamlikitkul Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Cinnamon stomachic mixture, functional dyspepsia, simethicone

Abstract

Health care personnel at a community hospital have used cinnamon stomachic mixture for treatment of patients with functional dyspepsia for many years and they claimed that cinnamon stomachic mixture was effective without any supportive evidence.
Objective: To determine the efficacy, safety, patients’ compliance and satisfaction with the treatment of cinnamon stomachic mixture.
Methods: This was a randomized controlled study in 318 adults with functional dyspepsia presenting to 6 community hospitals. The patients were randomized to receive 105 mg of simethicone three times a day or 30 ml of cinnamon stomachic mixture three times a day for 7 to 14 days. The patients were evaluated for improvement of symptoms, compliance to medication and patients’ satisfaction with the treatment. The data were analysed by descriptive statistics, chi-square statistics, student t test, analysis of variance and non-parametric tests where appropriate.
Results: One hundred and fifty patients received simethicone and 168 patients received cinnamon stomachic mixture. The baseline characteristics of the patients in both groups were not significantly different. The patients’ compliance to simethicone and cinnamon stomachic mixture was 82% and 89.3% respectively (p=0.09). The severity of the symptoms after treatment and the response rates were not significantly different between both groups. Side effects were observed in 9.3% and 9.5% in the simethicone group and the cinnamon stomachic mixture group respectively. Most of the patients in both groups were satisfied with the treatments they received. The cost of a 14-day course of cinnamon stomachic mixture was 36 baht compared with 84 baht for that of simethicone.
Conclusion: Cinnamon stomachic mixture is effective and safe for the treatment of the patients with functional dyspepsia similar to simethicone.

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Published

01-11-2006

How to Cite

Jindarat, S., Muangnoi, C. ., Changsiriporn, D. ., Platong, A. ., Thanamontra, B. ., Chiewchanwit, D. ., Vongvanvatana, V. ., Rongrungsri, N. ., Krittasilp, K. ., Kaewkong, . N. ., Kantawan, S. ., Virasombat, N. ., Mongkolporn, V. ., Prakobkij, W. ., Wanleepong, K. ., Maneekul, C. ., Benchakhanta, S. ., Boonpok, P. ., Kunnasut, W. ., Tongkleaw, L. ., Vatthanasak, . A. ., Mookkhan, J. ., Jatuporn, C. ., Tuntiprawan, K., Teerawongseree, S. ., Ussawasrisuwan, S. ., Thamcharoen, . P. ., Keawsontaya, T. ., Chuthaputti, A. ., Termviset, P. ., & Thamlikitkul, V. . (2006). Efficacy and Safety of Cinnamon Stomachic Mixture for Patients with Functional Dyspepsia. Siriraj Medical Journal, 58(11), 1103–1106. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/246001

Issue

Vol. 58 No. 11 (2006): November

Section

Original Article

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