Paragangliomas of the Head and Neck: A retrospective review at Siriraj Hospital

Authors

  • Anchalee Churojana Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Mayura Boonthathip Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Parvinee Suwanagool Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Carotid body tumor, glomus tumor, paragangliomas

Abstract

Objective: To analyze the distribution and radiological findings of paragangliomas of the head and neck region at Siriraj Hospital.

Methods: The cases with pathological proven of paragangliomas in the head and neck from January 1996 to December 2003 at Siriraj Hospital were retrospectively reviewed. Clinical presentation and radiologic findings in term of location, size, number, pattern of enhancement, vascularity and bony destruction were analyzed.

Results: There were 26 tumors among 22 patients which were 12 females and 10 males, with an average age of 47 years old. By locations, paragangliomas were found as carotid body tumor in 46.2%, glomus tympanicum in 11.5%, glomus vagale in 11.5%, glomus jugulare in 3.8%, glomus jugulotympanicum in 7.6% and rare locations in 19.2%. The unusual locations included sinonasal cavity, sphenoid sinus, supraglottic larynx, thyroid gland and posterior fossa. The presenting symptoms were neck mass in 53.8%, tinnitus in 26.9%, cranial nerve palsy in 19.2%, epistaxis in 3.8%, hoarseness of voice in 3.8%, severe headache in 3.8%. Multicentricity was found in 18%. Aggressive pattern was documented in 15.4%. The radiological findings of paragangliomas in usual locations were all characteristic homogeneous intensely enhanacement or hypervascularity (100%). Those in rare locations had also central necrosis (60%). Bony destruction was shown in 9.5% of usual locations and 40% of unusual locations. No any of lesions in rare locations had multicentricity.

Conclusion: Carotid body tumor is the most common paragangliomas in the head and neck region. Clinical presentation of a paraganglioma is related to location of the tumor. On the basis of the locations and radiographic characteristics, in common locations, imaging findings are characteristics and they may provide definite diagnosis, but in rare locations the radiological findings are not characteristics, and should be differentiating from other head and neck lesions.

Downloads

Published

01-02-2007

How to Cite

Churojana, A. ., Boonthathip, M. ., & Suwanagool, P. . (2007). Paragangliomas of the Head and Neck: A retrospective review at Siriraj Hospital. Siriraj Medical Journal, 59(2), 52–59. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/246032

Issue

Vol. 59 No. 2 (2007): Mar-Apr

Section

Original Article

License

Users are free to share, copy, and redistribute all articles published in the Siriraj Medical Journal (SMJ) in any medium or format as long as you follow the following terms:

  • Attribution — You must give appropriate credit, provide a link to the material, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the publisher endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.