Correlation between Subfascial Fat Loss and Decrease in Serum Insulin Levels

Authors

  • Pipop Jirapinyo Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Supawadee Likitmaskul Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Pipat Chiewvit Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Narumon Densupsoontorn Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Jeerunda Santiprabhob Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Chakraphan Susiva Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Renu Wongarn Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Nuchnoi Thamonsiri Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Computed tomography, obese teenager, subfascial fat, serum insulin, weight-reduction program

Abstract

Objective: To determine the association between reductions of fat from subcutaneous, intermuscular and subfascial compartment at thighs and improvement of serum insulin level.
Methods: A longitudinal, clinical intervention study of restricted energy with exercise was performed in 20 healthy, overweight teenagers (age: 10-15 y, BMI: 26-40 kg/m2). Fat distribution parameter (by dual-energy X-ray absorptiometry and computerized axial tomography at thigh), serum insulin, body weight were assessed at baseline and after 4 weeks.
Results: There are significant reductions in bodyweight, BMI, serum insulin, FGIR subfascial fat and intermuscular fat after 4 weeks. Loss of subfascial fat at thighs is significantly associated with decreasing levels of serum insulin in those who have initially abnormal high levels.
Conclusion: Losses of subfascial fat at thighs is associated with improvement of insulin levels in obese teenagers who are on 4 weeks of dietary restriction and moderate exercise.Â

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Published

01-05-2003

How to Cite

Jirapinyo, P., Likitmaskul, S. ., Chiewvit, P. ., Densupsoontorn, N. ., Santiprabhob, J. ., Susiva, C., Wongarn, R. ., & Thamonsiri, N. . (2003). Correlation between Subfascial Fat Loss and Decrease in Serum Insulin Levels. Siriraj Medical Journal, 60(3), 106–110. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/246365

Issue

Vol. 60 No. 3 (2008): May-Jun

Section

Original Article

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