Non-HDL-Cholesterol and Total Cholesterol to HDL-C Ratio in Abdominally Obese Adults in Phitsanulok

Authors

  • Surapon Tangvarasittichai Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Orathai Tangvarasittichai Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Sirilak Teeraputon Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Ratchaneewan Maneemaroj Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Wanvisa Boonlert Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Jirapas Jongjitwimol Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Watchanan Wongseana Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Panadda Jermsri Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Suwadee Meemark Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University
  • Nipaporn Sangaroon Department of Physical Therapy, Faculty of Allied Health Sciences, Naresuan University

Keywords:

Abdominal obesity, Non-HDLc, TC/HDLc ratio

Abstract

Objective: To compare non-HDLc and the TC/HDLc ratio in men and women with and without abdominal obesity (AO).
To evaluate the association of non-HDLc and the TC/HDLc ratio with the other risk factors and to estimate the non-HDLc
and TC/HDLc ratio level in both men and women with AO to establish the cutoff point by using ROC curve analysis.
Methods: Data (n=533) was used from adult Phitsanulok participants (aged ≥40 years) who came for their health check ups
in the service project. AO was defined as waist circumference (WC) of ≥90 cm for men and ≥80 cm for women. The ttest
was used to compare the difference in non-HDLc and the TC/HDLc ratio and other risk factors. The Pearson bi-variate
correlation analysis was used to quantify the association of non-HDLc and the TC/HDLc ratio with blood pressure (BP) and
other lipids.
Results: Both non-HDLc and the TC/HDLc ratio levels were elevated in men and women with AO. However in men
neither two variables were significantly different, both non-HDLc and TC/HDLc ratio levels were elevated in men with and
without AO. Non-HDLc and the TC/HDLc ratio were significantly higher in women with AO than without AO. We used
the ROC curve to estimate cutoff values for non-HDLc and TC/HDLc ratio levels and also other lipids in our Thai subjects.
The area under the curve of ROC of triglycerides may be superior to other risk markers for men and women in the present
study.
Conclusion: Both non-HDLc and the TC/HDLc ratio were elevated in men and women with AO. WC and BP may be
better associated markers for non-HDLc and the TC/HDLc ratio for men participants. The combination of elevated non-
HDLc, the TC/HDLc ratio, BP, and WC may identifiy a group of participants with more marked risk of CVD, metabolic
syndrome, and type 2 diabetes.

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Published

01-03-2009

How to Cite

Tangvarasittichai, S., Tangvarasittichai, O. ., Teeraputon, S. ., Maneemaroj, R. ., Boonlert, W. ., Jongjitwimol, J. ., Wongseana, W. ., Jermsri, P. ., Meemark, S. ., & Sangaroon, N. . (2009). Non-HDL-Cholesterol and Total Cholesterol to HDL-C Ratio in Abdominally Obese Adults in Phitsanulok. Siriraj Medical Journal, 61(2), 82–87. Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/246580

Issue

Vol. 61 No. 2 (2009): Mar-Apr

Section

Original Article

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