Effectiveness of the Four-Frequency Protocol of Repetitive Peripheral Magnetic Stimulation (rPMS) for Chronic Pain

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Virachat Sanansilp
Pramote Euasobhon
Quyen V. Than
Pranee Rushatamukayanunt
Sukunya Jirachaipitak
Sarasate Eiamtanasate


Objective: Repetitive peripheral magnetic stimulation (rPMS) is a noninvasive method of delivering a magnetic field to the periphery other than the brain. The treatment has shown positive outcomes for chronic pain and provides many advantages. This study investigated the effectiveness of the four-frequency protocol of rPMS in patients with chronic pain.
Materials and Methods: A retrospective review was conducted of patients with chronic pain treated with the four-frequency protocol. Data on patient demographics, pain characteristics, quality of life, and satisfaction were collected and analyzed.
Results: Forty-eight patients (174 sessions) were eligible for analysis. Most patients (81%) were diagnosed with chronic neuropathic pain. Upon completing the 4-week course of treatment, the mean � SD of percentage of pain reduction was 49.7% � 34.8%. The pain score also significantly decreased from baseline (mean difference, 3.3; 95% CI, 2.5�4.1; P < 0.001). Responses to treatment were observed for most patients (79.2%) and most treatment sessions (87.4%). For immediate effectiveness, the mean � SD of percentage of pain reduction at the end of each treatment session was 46.2% � 27.6%. Improvements in mood, function, and sleep were reported by 75.8%, 77.3%, and 79.5% of patients, respectively. Furthermore, most patients (72.5%) expressed satisfaction with the treatment.
Conclusion: The four-frequency protocol of rPMS for patients with chronic pain significantly reduced their pain scores for immediate effect and after the 4-week treatment course. A positive treatment response, an improved quality of life, and satisfaction with the therapy were found for nearly 80% of the patients.


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How to Cite
Sanansilp, V. ., Euasobhon, P. ., Than, Q. V. ., Rushatamukayanunt, P. ., Jirachaipitak, S. ., & Eiamtanasate, S. . (2022). Effectiveness of the Four-Frequency Protocol of Repetitive Peripheral Magnetic Stimulation (rPMS) for Chronic Pain. Siriraj Medical Journal, 74(8), 518–529. https://doi.org/10.33192/Smj.2022.62
Original Article


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