Effectiveness of a Brain Training Program on the Cognitive Function of Sepsis Survivors: A Randomized Controlled Trial Study

Authors

  • Jutarat Kiangsungnoen Adult and Gerontological Nursing, Faculty of Nursing, Mahidol University, Bangkok 10700, Thailand
  • Wimolrat Puwarawuttipanit Department of Medical Nursing, Faculty of Nursing, Mahidol University, Bangkok 10700, Thailand
  • Chontira Riangkam Department of Medical Nursing, Faculty of Nursing, Mahidol University, Bangkok 10700, Thailand
  • Yong Rongrungruang Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand

DOI:

https://doi.org/10.33192/smj.v77i3.272129

Keywords:

Sepsis survivors, brain training program, cognitive functions

Abstract

Objective: This study aimed to evaluate the effectiveness of a brain training program designed to enhance the cognitive function of sepsis survivors.

Materials and Methods: We conducted a single-blind randomized controlled trial at a tertiary care hospital involving 67 participants aged over 18 years with participants randomly assigned to two groups, an experimental group (n=33) receiving the brain training program, and a control group (n=34) receiving standard care only. We measured cognitive function at three different time points: Baseline, Week 6, and Week 12, using the Thai Mental State Examination for testing and repeated measure ANOVA for statistical analysis.

Results: The experimental group had a higher mean cognitive function score at Week 6 posttest than at pretest. At Week 12, the mean cognitive function score increased significantly compared with that at pretest (F = 442.279, p < .001) and the experimental group had a higher mean cognitive function score than the control group (F = 104.905, p < .001).

Conclusion: The brain training program significantly increased the cognitive function levels of sepsis survivors in 6–12 weeks. The result of this study shows the benefits of a brain training program in increasing cognitive functions. Therefore, such a brain training program should be implemented among sepsis survivors to improve their cognitive functions.

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Published

01-03-2025

How to Cite

Kiangsungnoen, J. ., Puwarawuttipanit, W. ., Riangkam, C. ., & Rongrungruang, Y. . (2025). Effectiveness of a Brain Training Program on the Cognitive Function of Sepsis Survivors: A Randomized Controlled Trial Study. Siriraj Medical Journal, 77(3), 209–219. https://doi.org/10.33192/smj.v77i3.272129

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