Severe Rhabdomyolysis from Pharmacokinetic Interaction of Statin in Patient with Diabetic Nephropathy: A Case Report

Authors

  • Teerapong Monmaturapoj Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, UBon Ratchathani University, Ubon Ratchathani 34190.

Abstract

Rhabdomyolysis is a potentially life-threatening syndrome characterized by muscle necrosis and the release of intracellular muscle contents into systemic circulation. The authors report a rhabdomyolytic patient with chronic kidney disease who had reduction of renal function owing to undiagnosed hypothyroidism, from drug interaction of simvastatin with gemfibrozil and amlodipine.

Keywords: Rhabdomyolysis, acute renal failure, drug interaction, statins

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Published

05-10-2015

How to Cite

Monmaturapoj, T. (2015). Severe Rhabdomyolysis from Pharmacokinetic Interaction of Statin in Patient with Diabetic Nephropathy: A Case Report. Siriraj Medical Journal, 67(5). Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/55225

Issue

Vol. 67 No. 5 (2015): September-October

Section

Case Report

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