Left Ventricular Ejection Fraction Analysis in an Equilibrium Cardiac Gated Blood Pool Study: Is the Same Software Package Really Needed to Follow Up the Same Patient?

Authors

  • Tanyaluck Thientunyakit Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700.

Abstract

Objective: To compare the left ventricular ejection fraction (LVEF) estimation using two commercial software packages used in our hospital and factors which may correlate to LVEF result.
Methods: LVEF results using EF analysis (GE Healthcare, Wisconsin, USA) and Syngo MI (Siemens Medical Solution USA Inc., Illinois, USA) in 120 patients were compared. The correlation and difference of LVEF analysis between software packages were evaluated using correlation coefficient and Bland-Altman analysis, respectively.  Potential factors for significant difference in LVEF were identified by regression analysis.
Results: The mean LVEF estimated by two software packages were highly correlated (ICC =0.853) and statistically significant (p<0.001). Subgroup analysis in each individual software showed slight decrease in correlation of LVEF between software packages (ICC=0.791-0.793), but still had statistical significance (p<0.001). Intra-and inter-operator variability assessments showed very high correlation of LVEF obtained from both software packages with statistical significance (p<0.001). Factors correlated with significant difference in LVEF were end diastolic area, end systolic count, end systolic area, and background count.
Conclusion: LVEF analysis from GBP study using different software packages is highly correlated with only minimal difference, thus, it may be reasonably interchangeable during follow up without significant clinical impact. However, operators should be aware the importance of precise left ventricular and background region generation to prevent technical errors.

Keywords: LVEF, cardiac gated blood pool, software analysis

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Published

31-08-2015

How to Cite

Thientunyakit, T. (2015). Left Ventricular Ejection Fraction Analysis in an Equilibrium Cardiac Gated Blood Pool Study: Is the Same Software Package Really Needed to Follow Up the Same Patient?. Siriraj Medical Journal, 67(4). Retrieved from https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/55231

Issue

Vol. 67 No. 4 (2015): July-August

Section

Original Article

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