Association Between on Screening for Thalassemia by OF with MCV/MCH of Red Blood Cell Indices In Married Couples Who Antenatal Care, Chaturaphak Phiman Hospital

Abstract

Objective : The aim of experimental research was to relationship between thalassemia screening results by OF and MCV / MCH screening.

Methods : 93 of participants were married couple who came to the antenatal clinic at Chaturaphak Phiman Hospital from December 2017 to February 2018, The research instruments were composed of Mindray automatic blood count monitor model BC 5380 and the OF reagent. Data were collected using a record form which passed content validation by experts. Descriptive statistics were analyzed by percentage, mean, standard deviation and inferential statistics such as chi-square.

Results : OF tests performed more negative than MCV / MCH tests 56.7% and 9.7% respectively. But MCV / MCH tests were more positive than OF, 90.3% and 43.5% respectively, when examining the relationships, it was found that OF test was related to the MCV / MCH test (p = 0.001).

Conclusions : This study suggest that OF tests were related to MCV / MCH tests But from the relationship between OF and MCV / MCH tests, MCV / MCH was much more positive than OF. It was possible that the MCV / MCH cut off may be too wide, resulting in quite a false negative. More research should be conducted in this area in order to save further screening budgets and OF tests was read by the naked eye which may vary according to reader further research should be conducted to find.