Lymph node ratio is a prognostic factor in breast cancer with axillary node dissection.
Keywords:
Breast cancer, Metastatic lymph node ratio, LNR, Khon kean hospitalAbstract
Objective : To study the prognostic value of LNR in breast cancer in Khon Kaen hospital.
Methods : This study is a retrospective analytical study. The patients with breast cancer are performed modified radical mastectomy. The medical record and pathological report are reviewed.
Result : All patients are women. Age ranging from 34-78 years. (Mean 51.49+/-9.87 years). Five-year survival is 73.7%. This study shows histological grade, HER-2 positive, LNR, N stage, M stage, Pathological stage, Adjuvant therapy, Endocrine therapy are statistically significant correlated with overall survival. But ER positive, PR positive, Lymph-vascular invasion, resection margin positive, T stage, Ki-67 are not correlated to overall. In the N1 breast cancer group, the LNR is an independent prognostic factor better than the N stage.
conclusion : The LNR is correlated with overall survival. The LNR could be an independent prognostic factor especially in N1 breast cancer.
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