Factors associated with mortality among patients with acute ST-elevation myocardial infarction (STEMI) receiving the thrombolytic drug (Streptokinase) in Khon Kaen Hospital
Keywords:
Acute STEMI, Streptokinase, Mortality FactorsAbstract
Objective : To identify prognostic factors of death among patients with acute STEMI who were treated with streptokinase at Khon Kaen Hospital.
Method : We conducted a cross-sectional analytical study, including patients with STEMI who received streptokinase at Khon Kaen Hospital between January 1, 2019, and December 31, 2021. We used univariable and multivariable logistic regression analysis to identify factors associated with death and reported them as crude odds ratio (OR), adjusted OR, and their 95% confidence intervals (95% CI).
Result : A total of 524 patients were studied, of whom 77.0% were male, with an average age of 63.2 ± 11.3 years. There were 41 (7.8%) deaths. Multivariate analysis identified that significant factors associated with mortality were female gender (Adj OR 6.25; 95% CI 2.00-20.00) and onset-to-needle time of 120-360 minutes (Adj OR 12.12; 95% CI 2.00-73.41).
Conclusion : Factors affecting the mortality of STEMI patients treated with streptokinase at Khon Kaen Hospital include female gender and an onset-to-needle time of 120-360 minutes.
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