Comparison of Survival Rates in Elderly Patients with Hip Fractures Undergoing Proximal Femoral Nail Antirotation (PFNA) or Hip Arthroplasty Within and Beyond 72 Hours at Bang Pa-in Hospital
Keywords:
Hip Arthroplasty, Proximal Femoral Nail Antirotation (PFNA), Survival RateAbstract
Objective: To compare survival rates and identify factors associated with survival among elderly patients with hip fractures who underwent either proximal femoral nail antirotation (PFNA) fixation or hip arthroplasty, stratified by surgery performed within and beyond 72 hours after fracture.
Methods: This retrospective cohort study included 140 patients aged ≥60 years who underwent PFNA fixation or hip arthroplasty for hip fractures at Bang Pa-in Hospital between 2018 and 2022. Patients were categorized into two groups based on surgical timing: ≤72 hours and >72 hours.
Results: Patients in the >72-hour group had significantly higher mean age and Charlson Comorbidity Index scores than those in the ≤72-hour group (p < 0.01). The delayed surgery group had a significantly higher mortality rate (28.57% vs. 12.86%, p = 0.02) and overall complication rate (28.57% vs. 8.57%, p = 0.002). Additionally, patients operated within 72 hours had significantly higher Activities of Daily Living (ADL) scores at weeks 6 and 12 postoperatively (p < 0.05). However, multiple Cox regression analysis revealed no statistically significant association between surgical timing and survival (adjusted HR = 0.54, 95% CI: 0.19–1.52, p = 0.24).
Conclusion: Although the multiple Cox regression analysis did not demonstrate a statistically significant association between surgery within 72 hours and mortality, early surgery was associated with a lower incidence of postoperative complications and better functional recovery of the hip compared with delayed surgery. Therefore, performing PFNA fixation or hip arthroplasty within 72 hours should be considered when clinically feasible and in the absence of contraindications to optimize patient outcomes.
References
Emmerson BR, Varacallo MA, Inman D. Hip fracture overview. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023.
Ensrud KE. Epidemiology of fracture risk with advancing age. J Gerontol A Biol Sci Med Sci. 2013;68(10):1236-1242.
Santini S, Rebecatto, Bolgan I, et al. Hip fractures in elderly patients treated with bipolar hemiarthroplasty. Comparison between cemented and cementless implants. J Orthop Traumatol. 2005;6:80–7.
Roberts SE, Goldacre MJ. Time trends and demography of mortality after fractured neck of femur in an English population, 1968-98:database study. BMJ 2003;327:771-5.
Goldacre MJ, Roberts SE, Yeates D. Mortality after admission to hospital with fractured neck of femur: database study. BMJ 2002;325:868-9.
Daraphongsataporn N, Saloa S, Sriruanthong K, Philawuth N, Waiwattana K, Chonyuen P, et al. One-year mortality rate after fragility hip fractures and associated risk in Nan, Thailand. Osteoporosis and Sarcopenia.2020 jun;6(2):65-70.
ปริปริณ ศรีหลังศักดิ์. ความชุก อัตราการป่วยตายและปัจจัยที่เกี่ยวข้องกับผู้ป่วยที่มีภาวะกระดูกข้อสะโพกหักในผู้สูงอายุของโรงพยาบาลบึงกาฬ. Udon Thani Hosp Med J. 2024;32(1):71-83.
วัชระ วิไลรัตน์. กระดูกต้นขาหัก (Fracture of the Proximal part of femur) [Internet]. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย. Available from: http://ortho.md.chula.ac.th/student/SHEET/fxfemur.html. Accessed [2 กรกฎาคม 2567].
กีรติ เจริญชลวานิช. Hemiarthroplasty and Total hip arthroplasty in Orthopaedic Nursing Care. ใน: Advance Orthopaedic Nursing Care เนื่องในวาระครบรอบ "ศิริราช 120 ปี". กรุงเทพฯ: ภาควิชาศัลยศาสตร์ออร์โธปิดิกส์และกายภาพบำบัด คณะแพทยศาสตร์ศิริราชพยาบาล มหาวิทยาลัยมหิดล; 2551.
Rogmark C, Johnell O. Primary arthroplasty is better than internal fixation of displaced femoral neck fractures: a meta-analysis of 14 randomized studies with 2,289 patients. Acta Orthop. 2006;77(3):359-367.
Mitchell SM, Chung AS, Walker JB, Hustedt JW, Russell GV, Jones CB. Delay in Hip Fracture Surgery Prolongs Postoperative Hospital Length of Stay but Does Not Adversely Affect Outcomes at 30 Days. J Orthop Trauma. 2018;32(12):629-633.
Simunovic N, Devereaux PJ, Sprague S, et al. Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis. CMAJ. 2010;182(15):1609-1616.
Orosz GM, Magaziner J, Hannan EL, Morrison RS, Koval K, Gilbert M, McLaughlin M, Halm EA, Wang JJ, Litke A, Silberzweig SB, Siu AL. Association of timing of surgery for hip fracture and patient outcomes. JAMA. 2004 Apr 14;291(14):1738-43.
Suttaphakti B, Tananoo S, Thremthakanpon W, Wanitcharoenporn W. Comparison of One-year Survival Rate of Hip Arthroplasty Performed within and After 72 Hours in Elderly Femoral Neck Fracture. J Southeast Asian Orthop. 2023 Jan 27;47(2):3–10.
Moja L, Piatti A, Pecoraro V, Ricci C, Virgili G, Salanti G, et al. Timing matters in hip fracture surgery: patients operated within 48 hours have better outcomes. A meta-analysis and meta-regression of over 190,000 patients. PloS One. 2012;7(10):e46175.
Liu L, Gao F, Liu Y, Xing Q, Li S, Li W, et al. Association of surgery time and early curative effect for elderly patients with femoral neck fracture in China. Biomed Res. 2017 Jun 1;28(10):4450–5.
Doruk H, Mas MR, Yildiz C, Sonmez A, Kýrdemir V. The effect of the timing of hip fracture surgery on the activity of daily living and mortality in elderly. Arch Gerontol Geriatr. 2004;39(2):179–85.
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