Development of National Compliance Monitoring Authority to OECD GLP Mutual Acceptance of Data on Chemical Assessment

Development of Compliance Monitoring Authority to OECD GLP Mutual Acceptance of Data on Chemical Assessment

Abstract

         In 2010, the National Assembly of Thailand decided for the country to become a provisional adherent of the Organization for Economic Co-operation and Development (OECD). This decision was made in relation to the Council Acts related to the Mutual Acceptance of Data (MAD) in the Assessment of Chemicals, with important conditions for the National Compliance Monitoring Authority (CMA) to undergo OECD evaluations. The Bureau of Laboratory Quality Standards, Department of Medical Sciences, as the National Compliance Monitoring Authority (CMA) in Thailand, has developed objectives to pass the on-site evaluation and become a full adherent to the MAD. The development comprised important components simultaneously: CMA (inspectors, personnel, GLP compliance program, and the archive system), as well as test facility compliance with the OECD Principles of Good Laboratory Practice (GLP), OECD Test guidelines, and OECD Council Acts. As a result, in 2018, CMA underwent an on-site evaluation by OECD members. On September 7, 2020, the OECD Council decided that Thailand to become a full adherent to MAD. The benefits as a full adherent were providing the same rights and obligations in Mutual Acceptance of Data (MAD) in the Assessment of Chemicals without duplicative testing, saving time and resources, help to avoid the creation of technical trade barriers, and further improve the protection of human health and the environment, and it is increasing the potential of sponsors to be more competitive in the international trade. Now in 2025, 7 test facilities have been registered in compliance with OECD GLP. However, CMA is further required for continuous development to upgrade operation standards to the same level as other OECD members.