The Association Between HbA1c and Severity of COVID-19 Patients in Nakhonpathom Hospital
Keywords:
COVID-19, diabetes mellitus, mortality, HbA1c, blood sugarAbstract
Objective: Since December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan city and has become a pandemic. Many affected patients had mild symptoms, while some people had severe symptoms or died. Uncontrolled diabetes tends to be one of poor prognostic factor in many studies1-3 This study aimed to examine the relationship between HbA1c levels and the severity of COVID-19 patients in Nakhonpathom Hospital
Methods: A single-center, retrospective observational study was conducted. Baseline characteristics; blood chemistry; and severity parameters such as chest x-ray, oxygen saturation, and patient outcomes were collected
Results: Since May to September 2022, 595 COVID-19 patients with diabetes mellitus were included. Of total, 29.3% of patients were newly diagnosed of diabetes mellitus. We compared between severe group (patients who required oxygen support, SpO2 ≤94%, or disease progression or dead) and non-severe group and correlation analysis was performed. The effect between higher body weight and severity of COVID-19 increased significantly (Mean ± SD 69.97 ± 17.54 vs 75.06 ± 20.75; p = .03). However, higher HbA1c level, blood sugar, and BMI related insignificantly with COVID-19 severity
Conclusion: The correlation between high HbA1c and severity of COVID-19 is still inhomogeneous. Our study demonstrates that patients with high HbA1c was insignificant relate to severe COVID-19.
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ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์
