Prevalence of Metabolic Syndrome in Gout Patients at Nakhonpathom Hospital
Keywords:
gout, metabolic syndrome, prevalence, hyperruricemiaAbstract
Objective: The aim was is to investigate the prevalence of metabolic syndrome (MetS) among patients with gout and to determine the relationship between hyperuricemia and MetS.
Methods: This is a retrospective study of patients aged ≥18 years and had been diagnosed with gout between 23 September 2017 and 23 September 2021 in Nakhonpathom Hospital.
Results: During the study period, there were 96 patients diagnosed with gout. Of these, 62 had MetS (64.6%).
Pearson’s chi-square test was used to determine the associations between serum uric acid level and MetS. P-value < .05 was set as the statistical significance level. Smoking, chronic alcoholic drinking, exercise, uncontrolled gout (defined as at least 3 flares in the past year, tophaceous gout, hyperuricemia) were associated with MetS.
Multiple regression analysis showed that serum uric acid level had a significant impact on waist circumference, fasting plasma glucose, fasting triglycerides, and high-density lipoprotein cholesterol (p-value < .05).There were no significant associations between systolic and diastolic blood pressure with serum uric acid level (p-value > .05).
Conclusion: In this study, uncontrolled gout and hyperuricemia were found to be associated with MetS. Control of these conditions might be beneficial to prevent or reduce the development of MetS.
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ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์
