ภาวะเลือดออกในโพรงสมอง ในทารกเกิดก่อนกำหนด
Abstract
Background: Intraventricular hemorrhage are frequency causal in preterm neonates, especially very low birth weight neonates < 1,500 grams. Intraventricular hemorrhage increases morbidity and mortality in neonates.
Objective: To determine prevalence and associated factors of intraventricular hemorrhage in preterm neonates in neonatal care unit at Khonkaen hospital.
Material And Methods: A descriptive retrospective study of intraventricular hemorrhage in preterm neonates was conducted on neonatal care unit at Khonkaen hospital from 1st January 2014 to 31th December 2016.
Result: In total 235 preterm neonates had screening cranial ultrasound, Inborn 177 (75.3%) and Outborn 58 (24.7%) neonates. The prevalence of intraventricular hemorrhage in preterm neonates was 42.1%. There were 69 (29.4%), 10 (4.3%), 19 (8.0%) and 1 (0.4%) were diagnosed as Intraventricular hemorrhage grade I, II, III and IV respectively. Five variables demonstrated statistically associations with IVH as independent risk factors: Gestational age (odds ratio, 0.51; 95% CI; 0.29 to 0.87; P = 0.01), RDS (odds ratio, 3.05; 95% CI; 1.10 to 8.42; P = 0.03), Vasopressor drugs (odds ratio, 1.93; 95% CI; 1.10 to 3.37; P = 0.02), NEC (odds ratio, 3.34; 95% CI; 1.22 to 9.12; P = 0.01) and Seizure (odds ratio, 0.40; 95% CI; 0.34 to 0.47; P = 0.01). However no variable demonstrated statistically associations with IVH as independent risk factors if considered associations between variables (P < 0.05).
Conclusion: The study found that prevalence of intraventricular hemorrhage in preterm neonates was 42.1%, similar or even higher prevalence to that report in other study. Our study support the screening cranial ultrasound performed in all preterm neonates for early detection of intraventricular hemorrhage and closed follow up, to minimize further brain injury due to its complication.
Keywords: Intraventricular hemorrhage, preterm neonate
References
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