Electrodiagnosisfindings in Guillain- Barré syndrome
Abstract
Introduction : Patients withGuillain-Barré syndrome (GBS) usually present with acute flaccid paralysis. For good outcome, severely affected patients need early and specific treatment. Electrodiagnosis study is a tool for diagnosis, differentiating GBS subtypes and predict outcome of GBS.
Objective : To identify electrodiagnosis findings and classify GBS subtypes using electrodiagnostic criteria.
Material and methods : A retrospective descriptive study enrolled GBS patients admitting in KhonKaenhospital and underwent electrodiagnostic study (EDx) between January 1, 2013 and October 31, 2018 was done. Demographic data, clinical data and electrodiagnosis data were obtained from patient’s medical record.
Results : 94 patients with GBS were recruited, 52 were male and 42 were female. Their mean age was 45.1 ±19.2 years. Clinical presentations were tetraparesis(92.6%), glove and stocking numbness (75.5%) and dyspnea and ventilator needed(26.6%). GBS disability score at admission was 3.9 ± 0.8. GBS disability score before discharge was 3.5 ± 1.4. Eight patients died (8.5%). Most common EDx finding is an abnormal motor nerve conduction study 92.6% (87patients). Needle EMG study was perform in 81 patients and 29.6% showed signs of axonal denervation. GBS subtypes classified by electrodiagnostic criteria demonstrated axonal GBS 51.1%, Acute inflammatory demyelinating polyradiculoneuropathy 30.9%, equivocal 10.6% and normal 7.4%.
Conclusions : An axonal GBS subtype is the most common type of GBS in KhonKaen hospital. Early electrodiagnostic study within the first 7 days after onset of symptoms is useful for diagnosis and classify GBS subtypes.
Keywords : Guillain- Barré syndrome, Electrodiagnosis
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