Computed Tomography Findings of the Brain in Adults with First Seizure at Thabo Crown Prince Hospital

Authors

  • อภิวิชญ์ กุดแถลง

Abstract

Objective  :  Study  to Computed Tomography Findings of the Brain in Adults  with First Seizure at Thabo Crown Prince Hospital 

Methods: A retrospective chart review was conducted on all adult patients with first seizure presenting to Thabo Crown Prince Hospital ED over a 1-year period (June 2017 through June 2018). Electronic patient records were reviewed for demographics, neuroimaging, and laboratory test results.

 Results: 205 patients were included in study. Patients with history of previous seizure, head injury, electrolyte abnormalities, alcohol/drug intoxication were excluded from study. The mean age in our series was 52.21 years. There were 67.8 % males and 32.2 % were female. Generalized seizure was seen in 53.4 % of patients whereas focal seizure was seen in 46.3 % of patients. Abnormal CT scan was found in 41.9 % of patients with first episode of seizure. CT scan was abnormal in 71.6 % of patients with focal seizure. Only 16.4 % of patients with generalized seizure had abnormal CT scan.

 Conclusion: Poststroke sequelae was the commonest abnormality detected on CT scan which was found in 12.2 % of patients. Old surgery/old trauma sequelae was the commonest abnormality detected in younger population (42.1 %) while poststroke sequelae was common in older patients found in 37.3 % of patients. CT scan of the brain should be done as a routine investigation in all patients with first seizure. As CT scan is more easily available and cheaper than MRI, CT is preferred technique of neuroimaging and plays an important role as a preliminary tool in radiological assessment of patients presenting with first seizure.

Keywords: CT scan, first seizure, poststroke sequelae

References

American College of Emergency Physicians (ACEP). Clinical Policy: Critical issues in the evaluation of adult patients presenting to an emergency department with seizures. Ann Emerg Med 2004; 43: 605-25.

Huff JS, Morris DL, Kothari RU, Gibbs MA. Emergency department management of patients with seizures: a multicenter study. Acad Emerg Med 2001;8:622–8.

Hauser WA, Annegers JF, Kurland LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia 1993;34:453–68.

Annegers JF, Hauser WA, Lee JR, Rocca WA. Incidence of acute symptomatic seizures in Rochester, Minnesota, 1935-1984. Epilepsia 1995;36:327–33.

Sempere AP, Villaverde FJ, Martinez-Menendez B, Cabeza C, Pena P, Tejerina JA. First seizure in adults: a prospective study from the emergency department. Acta Neurol Scand 1992;86:134–8.

Tardy B, Lafond P, Convers P, et al. Adult first generalized seizure: etiology, biological tests, EEG, CT scan, in an ED. Am J Emerg Med 1995;13:1–5.

Hopkins A, Garman A, Clarke C. The first seizure in adult life. Value of clinical features, electroencephalography, and computerised tomographic scanning in prediction of seizure recurrence. Lancet 1988;1:721-6.

Ramirez-Lassepas M, Cipolle RJ, Morillo LR, Gumnit RJ. Value of computed tomographic scan in the evaluation of adult patients after their first seizure. Ann Neurol 1984;15(6):536-43.

Young AC, Costanzi JB, Mohr PD, Forbes WS. Is routine computerised axial tomography in epilepsy worthwhile? Lancet 1982;1446-7.

Rosenthal RH, Heim ML, Waeckerle JF. First time major motor seizures in an emergency department. Ann Emerg Med 1980; 9: 242-5.

Mc Fadyen MB. First seizures, the epilepsies and other paroxysmal disorders prospective audit of a first seizure clinic. Scott Med J 2004;49(4): 126-30.

Grunewald RA, Chroni E, Panayiotopoulos CP. Delayed diagnosis of juvenile myoclonic epilepsy. J Neurol Neurosurg Psychiatry 1992; 55: 497-9.

Krumholz A. Nonepileptic seizures: Diagnosis and management. Neurology 1999; S76-83.

Begley CE, Famulari M, Annegers JF, Lairson DR, Reynolds TF, Coan S, Dubinsky S, Newmark ME, Leibson C, So EL, Rocca WA. The cost of epilepsy in the United States: an estimate from population- based and survey data. Epilepsia 2000; 41: 342-52.

Rogel-Ortiz FJ. Epilepsy in the adult. A prospective study of 100 cases. Gac Med Mex 1999;135(4):363-8.

Oscar H. Del Brutto. CT findings in neurologically normal adults with a single generalized seizure. Journal of Epilepsy 1994; 7(1): 38-40.

Rajbhandari KC. Clinical profile of epilepsy in Nepal. In: Yagi K, ed. Epilepsy care in Asia. National Epilepsy Center, Shizuoka Medical Institute of Neurological Disorder, 2003:28-9.

Wood LP. Parisi M. Finch IJ. Value of contract enhanced CT scanning in the non-trauma emergency room patient. Neuroradiology 1990; 32: 261-4.

Baheti R, Gupta BD, Baheti R. A study of CT and EEG findings in patients with Generalized or Partial Seizures in western Rajasthan. JIACM. 2003;4(1):25-9.

Sa de Camargo EC, Koroshetz WJ. Neuroimaging of ischemia and infarction. NeuroRx. 2005;2:265–76.

Russo LS, Goldstein KH. The diagnostic assessment of single seizures. Is cranial computed tomography necessary? Arch Neurol 1983;40:744-6.

Downloads

Published

2019-07-13

How to Cite

กุดแถลง อ. (2019). Computed Tomography Findings of the Brain in Adults with First Seizure at Thabo Crown Prince Hospital. Mahasarakham Hospital Journal, 16(1), 146–155. retrieved from https://he02.tci-thaijo.org/index.php/MKHJ/article/view/203005