ผลลัพธ์การให้ยาไฮโดรคอร์ติโซนและไทอะมีนในผู้ป่วยติดเชื้อเมลิออยโดสิสในกระแสเลือด ในโรงพยาบาลมุกดาหาร

Authors

  • ราชันย์ จันทร์อ่อน -

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Abstract

Abstract

Background:Melioidosis septicemia is a high mortality rate. To determine the outcomes of hydrocortisone plus thiamine treatment in melioidosis septicemia patients. Method: Retrospective analytic study.Medical records of melioidosis septicemia patients admit from January 1st,2020 to December 31st,2020  in Mukdahan hospital were reviewed.   

Result: Of 90 cases reviewed, 46(51.1%) were hydrocortisone plus thiamine group and 44(48.9%) were standard care group. There were 28(60.9%) male, mean age(SD) 56.8(13.2) years, 31(67.2%) diabetic patients, 23(50.0%) cases of acute renal failure in hydrocortisone plus thiamine group and 24(54.5%) male, mean age(SD) 55.0(12.9) years, 24(54.5%) diabetic patients, 23(52.3%) cases of acute renal failure in standard care group. The mortality rate was 8.7% and 25.0% in hydrocortisone plus thiamine group and standard care group respectively (p=.038)

Conclusion: Melioidosis septicemia patients in hydrocortisone plus thiamine treatment group had lower mortality rate than standard care group.

 

Keywords: melioidosis septicemia, Burkholderia pseudomallei, hydrocortisone, thiamine

 

References

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Published

2022-04-30

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จันทร์อ่อน ร. (2022). ผลลัพธ์การให้ยาไฮโดรคอร์ติโซนและไทอะมีนในผู้ป่วยติดเชื้อเมลิออยโดสิสในกระแสเลือด ในโรงพยาบาลมุกดาหาร. Mahasarakham Hospital Journal, 19(1), 135–145. retrieved from https://he02.tci-thaijo.org/index.php/MKHJ/article/view/256117

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Vol. 19 No. 1 (2022): January-April

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