Screening test Cholangiocarcinoma by ultrasound Kudchum District, Yasothon

Abstract

This study was a retrospective descriptive  aimed to study and analyze the results of cholangiocarcinoma screening by ultrasound and study the epidemiology of liver cancer and cholangiocarcinoma. Populations are northeastern ≥ 40 years old in 3,864 risk group and Inclusion/Exclusion criteria during the year 2017-2019. Instrument in the study, ultrasound, patient medical records, demographic Information Form: Enrollment (CCA01), ultrasound form (CCA02) and Isan cohort database. Data were analyzed by descriptive statistics, frequency, mean, percentage, proportion test and 95% Cl The Results this study showed that, Populations were female 66.0%, mean 54 year old (SD±9.0) and graduated from primary degree 79.6%. They worked on the agricultural field 91.4% and never had the screening test for the eggs of liver fluke 52.6%. They have been tested to find liver fluke 53.0% and have treated with the anti-liver fluke 28.6%. Their relatives mostly have cholangiocarcinoma 77.5 %. The relatives who have cholangiocarcinoma are the first generation who are parents and siblings and have consumed river fishes with raw or semi-raw scales or raw fermented fish 94.5% which is similar to the cholangiocarcinoma screening and care program (CASCAP). Upper abdominal ultrasound abnormalities. Periductal fibrosis (PDF) was the most at 11.6%, followed by Fatty Liver 10.5%.Suspected cases 11 (300/100,000 population) were confirmed. Three patients were diagnosed with cholangiocarcinoma, one received surgery and one refused treatment. Ultrasound from CASCAP result detected similar during of PDF, fatty liver and Suspected Case, But when tested  statistical Z-test, it was found that the difference was statistically significant at the level (P<0.05). Epidemiological follow-up in Kud Chum district area, PDF was detected the most at Non Prathai 19.9%. Suspected Cases in 7 of 14 sites. Three of the confirmed cancer cases were in 3 of 7 areas where the Suspected Case was detected, requiring further in-depth study in the area.