Efficacy of cleome viscosa linn. extract hydrogel on acne inflammation.
Keywords:
extract cleome viscosa, hydrogel, acne inflammationAbstract
The objective of this study is to evaluate the efficacy of Cleome viscosa extract hydrogel on acne inflammation and to use the study’s findings to develop acne treatment products and skin inflammation remedies in the future. In this study, quasi-experimental research was designed to compare differences in two acne lesion groups - one acne group received cleome viscosa hydrodel treatment, one did not receive any treatment - on 30 healthy male and female volunteers aged 18 and above. The primary outcome is expressed in size, oedema, and erythema measurements before and 1, 2 and 72 hours after cleome viscosa hydrodel treatment. Statistical data analyses, namely descriptive data analysis and paired t-test, were then used to investigate acne lesion reduction differences between the two groups. The study’s findings show that acne group treated with Cleome viscosa extract hydrogel demonstrates faster inflammation reduction in total acne lesions than untreated group, with acne inflammation reduced at 72 hours equal to -99.33±3.65, -19.77±8.39 and -7.34±3.66% in size, oedema and erythema respectively, the difference has statistical significance (p-value=0.05) when compared with untreated group. Treated acne group also has better efficacy in acne lesion reduction, with effectiveness of -54.82±17.92, -9.24±9.35 and -6.67±4.20% in size, oedema, and erythema respectively. In conclusion, Cleome viscosa extract hydrogel is safe and effective on acne inflammation. Further study and development should be pursued
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารศูนย์ดัชนีการอ้างอิงวารสารไทย ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆบทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารศูนย์ดัชนีการอ้างอิงวารสารไทย ถือเป็นลิขสิทธิ์ของวารสารศูนย์ดัชนีการอ้างอิงวารสารไทย หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษรจากวารสารศูนย์ดัชนีการอ้างอิงวารสารไทยก่อนเท่านั้น
