FACTORS RELATED ADHERENCE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT SI CHAINGMAI HOSPITAL NONGKHAI PROVINCE

Abstract

Chronic Obstructive Pulmonary Disease causes 5^th death in Thailand. The treatment aims to reduce the severity of the disease and prevent long term acute exacerbation. The treatment will have good results that require the patient’s adherence. This research aimed to study the level of drug adherence among COPD patients and to study the predictive factors and their power of prediction in drug use of COPD patients at Sri Chiang Mai Hospital, by studying all 67 COPD patients. The general data were evaluated using frequency, percentage, mean, and standard deviation. Factors that affected drug adherence were analyzed using multiple regression analysis.

The results found that the majority of COPD patients had an appropriate level of drug adherence which was higher or equal to 6 scores, accounting for 62.70 percent. Genders, levels of education, and the perception of disease severity had a positive influence on drug adherence. Depression had a negative influence on drug adherence by decreased patient’s adherence. This could explain the variation in drug adherence by 46.20 percent with statistically significant at 0.05 (R² = 0.462, p <0.05).

          Therefore, pharmacist should coordinate with multidisciplinary teams to promote an appropriate level of drug adherence in COPD patients.