TREATMENT OUTCOME AND FACTORS ASSOCIATED SUCCESSFUL TREATMENT OF PATIENTS WITH DRUG RESISTANT TUBERCULOSIS OF YANGTALAT HOSPITAL, KALASIN PROVINCE

Abstract

This retrospective study aimed to investigate treatment outcomes and factors affecting the success rate of drug-resistant tuberculosis (DR-TB) treatment at Yang Talat Hospital, Kalasin Province. Purposive sampling was used to choose 40 DR-TB patients enrolled in the hospital's tuberculosis clinic during fiscal years 2014 and 2023. Medical record forms and the Department of Tuberculosis's (National Tuberculosis Information Program: NTIP) tuberculosis database system were used to collect data. Statistical analyses included descriptive statistics, Chi-square tests, and Fisher’s exact tests, with significance set at p-value < 0.05.

The results showed that most participants were male (87.50%), with the highest incidence in the 46–60 age group (40.00%). Half of the participants (50.00%) had a body mass index (BMI) of less than 18.50 kg/m². The treatment success rate was 65.00%, below the standard benchmark. A statistically significant factor influencing treatment success was age, with younger patients showing better treatment outcomes (p-value < 0.05).

The study suggests using interdisciplinary teams and community involvement to adopt systematic and cooperative approaches for DR-TB prevention and control. To improve treatment adherence and results, follow-up tools like telepharmacy services should also be created.