DEVELOPMENT OF INTERVENTION FOR IMPLEMENTING MEDICATION SAFETY STANDARDS IN HOSPITALS: KALASIN PROVINCE

Abstract

This Research and Development (R&D) study aimed to enhance drug safety standards in hospitals across Kalasin Province. The methodology was divided into three phases: 1) situational assessment of problems and development opportunities, 2) development of the “C-G-C-C-IT-M model” framework, and 3) evaluation of development outcomes. Data analysis involved comparing pre- and post-development scores using the Wilcoxon Signed-rank Test, supplemented by qualitative content analysis.

The results indicated that the primary areas failing to meet standards initially were primary care pharmacy, inpatient pharmaceutical care, and adverse drug reaction (ADR) monitoring. Systemic barriers included unclear policies and resource constraints. Following a six-month implementation of the developed model, the mean drug safety assessment score significantly increased from 1.28 to 3.08 (p-value< 0.05). Notable improvements were observed specifically in medication system management and medical supply inventory.

The study recommends scaling this model to all hospitals, supported by budget allocations for infrastructure and information technology (IT) development. Furthermore, central authorities should revise assessment criteria to be more flexible and aligned with the local context and specific capacities of hospitals at each level. Such adjustments are essential to ensure the long-term sustainability of drug safety systems and the efficiency of pharmaceutical care.