A Case Report of Multiple Angiolymphoid Hyperplasia with Eosinophilia

Authors

  • Apinya Sripha INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.
  • Sasathorn Singthong INSTITUTE OF DERMATOLOGY, DEPARTMENT OF MEDICAL SERVICES, MINISTRY OF PUBLIC HEALTH, BANGKOK, THAILAND.

Keywords:

Angiolymphoid hyperplasia with eosinophilia, ALHE, propranolol, surgical excision

Abstract

Angiolymphoid hyperplasia with eosinophilia (ALHE) is rare benign vasoproliferative disorder that most often affects the head and neck. We present an uncommon presentation of ALHE. A middle-aged Thai man presented with multiple red-brown dome-shaped papules on left shoulder, axilla and extended to scapular area, which were diagnosed as ALHE from typical histopathologic examination. In our case, we used a combination of oral propranolol and surgical excision for treatment.

References

Wells GC, Whimster IW. Subcutaneous angiolymphoid hyperplasia with eosinophilia. Br J Dermatol 1969;81:1-14.

Adler BL, Krausz AE, Minuti A, Silverberg JI, Lev-Tov H. Epidemiology and treatment of angiolymphoid hyperplasia with eosinophilia (ALHE): A systematic review. J Am Acad Dermatol 2016;74:506-12.e1.

Ben Lagha I, Souissi A. Angiolymphoid Hyperplasia With Eosinophilia. 2020 Sep 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing 2021;30844208.

Horst C, Kapur N. Propranolol: a novel treatment for angiolymphoid hyperplasia with eosinophilia. Clin Exp Dermatol 2014;39:810–2.

McClintic EA, Ting A, Yeatts RP. Oral propranolol as an alternative therapy for orbital angiolymphoid hyperplasia with eosinophilia. Ophthal Plast Reconstr Surg 2016;32:139–40.

Moss HB, Sines DT, Blatt J, Dutton JJ, Proia AD. Epithelioid hemangioma responsive to oral propranolol. Ophthal Plast Reconstr Surg 2012;28:88–90.

Zarbafian M, Ward CE, Zhang J, Macdonald J. Angiolymphoid Hyperplasia With Eosinophilia-Combination Treatment With Propranolol and Surgical Resection. Dermatol Surg 2018;44:1147-9.

Shenefelt PD, Rinker M, Caradonna S. A case of angiolymphoid hyperplasia with eosinophilia treated with intralesional interferon alfa-2a. Arch Dermatol 2000;136:837-9.

Aurello P, Cicchini C, D'Angelo F, Di Gioia CR, D'Amati G. Angiolymphoid hyperplasia with eosinophilia: a rare artery lesion. Anticancer Res 2003;23:3069-72.

Kempf W, Haeffner AC, Zepter K, et al. Angiolymphoid hyperplasia with eosinophilia: evidence for a T-cell lymphoproliferative origin. Hum Pathol 2002;33:1023-9.

Gonzalez-Cuyar LF, Tavora F, Zhao XF, et al. Angiolymphoid hyperplasia with eosinophilia developing in a patient with history of peripheral T-cell lymphoma: evidence for multicentric T-cell lymphoproliferative process. Diagn Pathol 2008;3:22.

Olsen TG, Helwig EB. Angiolymphoid hyperplasia with eosinophilia. A clinicopathologic study of 116 patients. J Am Acad Dermatol 1985;12:781-96.

Sommers Smith SK, Smith DM. Beta blockade induces apoptosis in cultured capillary endothelial cells. In Vitro Cell Dev Biol Anim 2002;38:298-304.

Downloads

Published

2021-11-17

How to Cite

Sripha, A., & Singthong, S. (2021). A Case Report of Multiple Angiolymphoid Hyperplasia with Eosinophilia. Thai Journal of Dermatology, 37(4), 167–172. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/252719

Issue

Vol. 37 No. 4 (2021): October - December

Section

Case Report

License

เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ

บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น