Result of Screening Colonoscopy Among person with positive FIT Fecal immunochemical test) in Prachuapkhirikhan Hospital

Authors

  • วุฒิกร วงษ์ศิลาทัย พ.บ., โรงพยาบาลประจวบคิรีขันธ์

Keywords:

FIT, CRC, polyp, advance adenoma, colonoscopy, screening, Thailand

Abstract

Objective: The aim was to find the false positive rate and positive predictive value of fecal immunochemical Test (FIT) positive patients for detecting polyps at risk of transformation (advance adenomas) and colorectal cancer (CRC).

Methods: A retrospective study was done among patients at the age of 50-70 years who had positive FIT in CRC screening program followed by colonoscopy at Prachuabkhirikhan Hospital from 1 September 2018 to 31 March 2020. The data included baseline characteristics, colonoscopic findings and pathological reports.

Results: A total of 367 patients positive FIT followed by colonoscopy at Prachuabkhirikhan Hospital. Fifty-five patients (15.0%) were excluded from study due to age, history of colorectal surgery, previous colonoscopy in 5 years, and loss of pathologic reports. A false positive rate was 41.7%. of total 58 Percent of positive predictive value, 13.8% were benign polyps, 28.5% were advance adenomas, 7.1% were CRC, and 9.0% were diverticular diseases. 

Conclusion: Nationwide CRC screening program in Prachuabkhirikhan Hospital has 35.6% positive predictive value to detect CRC and polyp at risk of transformation which could be benefit in treatment of colorectal cancer is false positive rate were 41.7%.

References

1. Imsamran W, Pattatang A, Supattagorn P, et al. Cancer in Thailand: Vol.IX, 2013-2015. Bangkok: Pronsup Printing; 2018.
2. Losiriwat V, Chaisomboon N, Pattana-Arun J, et al. Current colorectal cancer in Thailand. Ann Coloproctol. 2020; 36(2): 78-82.
3. National Cancer Institue of Thailand. HCospital-base cancer registry 2017. Bankok (Thailand): Pronsup Printing; 2017.
4. Hol L, van Leerdam ME, van Ballegooijen M, et al. Screening for colorectal cancer: randomized trial comparison guaiac-based and immunochemical fecal occult blood testing and flexible sigmoidoscopy. Gut. 2010; 59(1): 62-8.
5. van Rossum LG, van Rijn AF, Laheij RJ, et al. Random comparison of guaiac and immunochemical fecal occult blood test for colorectal cancer in a screening population. Gastroenterology. 2008; 135(1): 82-90.
6. Navarro M, Nicolas A, Ferrandez A, et al. A colorectal cancer population screening programs worldwide in 2016: An update. World J Gastroenterol. 2017; 23(20): 3632-42.
7. Parra-Blanco A, Gimeno-García AZ, Quintero E, et al. Diagnosis accuracy of immunochemical versus guaiac fecal occult blood test for colorectal cancer screening. J Gastroenterology. 2010; 45(7): 703-12.
8. Vart G, Banzi R, Minozzi S. Comparing participation rate between immunochemical and guaiac fecal occult blood test: a systematic review and meta-analysis. Prev Med. 2012; 55(2): 87-92.
9. Shaukat A, Mongin SJ, Geisser MS, et al. Long-term mortality after screening for colorectal cancer. N Engl J Med. 2013; 369: 1106-14.

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Published

2021-06-29

How to Cite

1.
วงษ์ศิลาทัย ว. Result of Screening Colonoscopy Among person with positive FIT Fecal immunochemical test) in Prachuapkhirikhan Hospital. Reg 4-5 Med J [internet]. 2021 Jun. 29 [cited 2026 Jan. 1];40(2). available from: https://he02.tci-thaijo.org/index.php/reg45/article/view/251829

Issue

Vol. 40 No. 2 (2021): Region 4-5 Medical Journal Vol.40 No.2 April-June 2021

Section

Original Article

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ลิขสิทธิ์บทความเป็นของผู้เขียนบทความ แต่หากผลงานของท่านได้รับการพิจารณาตีพิมพ์ลงวารสารแพทย์เขต 4-5 จะคงไว้ซึ่งสิทธิ์ในการตีพิมพ์ครั้งแรกด้วยเหตุที่บทความจะปรากฎในวารสารที่เข้าถึงได้ จึงอนุญาตให้นำบทความในวารสารไปใช้ประโยชน์ได้ในเชิงวิชาการโดยจำเป็นต้องมีการอ้างอิงถึงชื่อวารสารอย่างถูกต้อง แต่ไม่อนุญาตให้นำไปใช้ในเชิงพาณิชย์