Development and evaluation of hydrogels patch for Prasa Pew Pai Nok formulation

Abstract

Taxila scripture described diseases that presented with fever, rash and the recipe for treating fever. An interesting recipe that has made from the accessible ingredients which is a recipe for Prasa Pew Pai Nok consisting of Tiliacora triandra (Colebr.) Diels., Tamarindus indica L., and Derris scandens (Roxb.) Benth aqueous extract. The objective of this research is to develop and study the physical and chemical properties of hydrogel patches. It was found that the formula containing 10% glycerin as a plasticizer and 0.5% mucus extract from basil seeds had good physical properties. In addition, it had a neutral pH and had the highest swelling rate. Therefore, it was suitable to develop hydrogel patch to reduce fever. This formula composed 7.5%(w/w) herbal extracts. However, the bioactive composition of the substances as well as the stability of the product should be further studied in further clinical trials.