Prognostic Factors of Early and Late Mortality Rate in Community Acquired Sepsis

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Prakasit Tensit
Jayanton Patumanond
Sukee Phoblarp
Chalisa Nuntasunti
Thanita Montri

Abstract

Background: Sepsis is the majority cause of death in the world and Thailand. It consumes resource energy of practitioners’ material and money. Even though sepsis is the majority problem of mortality in public health but there is limitation of study in Thailand.
Objective: The purpose of this study was to determine the prognostic factors of early and late death in community acquired sepsis.
Methods: A retrospective cohort study in Medicine department at Sisaket hospital since October 2017 until April 2019.Two hundred and ninety patients with community acquired sepsis were recruited. The information data was analyzed from medical record.Early death set as death before 3 days and late death after 3 days.A multinomial regression analysis was performed to identify prognostic factors of early and late deaths.
Results: The overall mortality rate was 20.4 % in septic patients.The prognostic factors associated with early death in sepsis patients by multivariate were septic shock respiratory failure. The prognostic factors associated with late death were septic shock respiratory failure and hypoalbuminemia. The prognostic factors associated with both early and late death were septic shock and respiratory failure.
Conclusion: The complications of sepsis were the main factors associated with early and late death in sepsis patients. Prognostic factors of early and late deaths were septic shock and respiratory failure.
Keywords: community acquired sepsis, factors early death, late death

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