Comparison of Ultrasound Shear Wave Elastography and Transient Elastography for Diagnosis and Staging Hepatic Fibrosis in Patient with Chronic Hepatitis B and C
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Abstract
Background: Percutaneous liver biopsy is the standard of reference for clinical assessment of hepatic fibrosis. This is a highly accurate and reliable test. However, it is invasive and may cause complications. Ultrasound elastography is a noninvasive technique. The severity of liver fibrosis can be assessed. Fibroscan is a widely used test and has high detection accuracy.
Objective: To analyze the accuracy and consistency in the diagnosis and assessment of the severity of hepatic fibrosis from ultrasound elastography compared with fibroscan in patients with hepatitis B virus and C virus in Buriram Hospital.
Methods: Diagnostic study, cross sectional design, at the radiology department Buriram Hospital in patients diagnosed with hepatitis B and C between December 2020 and October 2021. All patients underwent ultrasound elastography and fibroscan to assess hepatic fibrosis staging. The results of the two methods were consistent with the complete perfect agreement and Weighted Kappa Coefficient.
Results: Total 79 patients, in both examinations had a complete perfect agreement of 82.2% and weight kappa=0.52 (p-value<0.001). F1-F2 group had weight kappa=0.53 (p-value<0.001) and F3-F4 group had weight kappa=0.03 (p-value=0.245).
Conclusion: Ultrasound shear wave elastography is accurate in diagnosing hepatic fibrosis in F1 and F2 stages, but has errors in hepatic fibrosis measurements F3 and F4 compared to fibroscans.
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