Outcome of Convulsive Status Epilepticus in Children
Main Article Content
Abstract
Background: Status epilepticus is considered as common neurological emergency in children.Morbidity and mortality are high and associated with seizure duration, inappropriate treatment and underlying disease.
Objective: To determine the mortality rate in children with convulsive status epilepticus (CSE) and factors that affect mortality rate.
Medthod: A retrospective study was conducted at Surin hospital. Eligible patients were infants or children diagnosed with convulsive status epilepticus (CSE) during January 1st 2009 to December 31st 2011. Research data included demographic data, etiology, treatment and clinical course were retrieved from patient medical database. Descriptive analysis and Fisher’s exact test were applied for data analysis.
Results: There were 37 patients (25 boys(67.7%) and 12 girls(32.4%)) with mean age of 4.3 yearsincluded in the study. Etiologies of CSE were remote symptomatic (37.8%), acute symptomatic (27%), febrile (21.6%) and cyptogenic (13.5%). Overall mortality was 13.5%. The mortality rate related to improper treatment (p = 0.01) and prolonged seizure duration (p = 0.02). Subsequent epilepsy was found in 6 patients (16.2%) and delayed development was found in 2 patients (5.1%).
Conclusions: Mortality rate from convulsive status epilepticus in children was 13.5% and causality was related to seizure duration before treatment and inappropriate treatment. The result hereby suggests prompt and appropriate termination of seizure may reduce mortality rate.
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References
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