Incidence, Clinical Presentation and Outcome of Hospitalized Children with Pneumonia Caused by Influenza Virus in Surin Hospital
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Abstract
Background: Community-acquired pneumonia (CAP) is a common cause of hospitalization in children younger than 5 years and mostly causative agents are viruses. Influenza is a common childhood illness but few studies have been conducted on Influenza-related pneumonia in children.
Objectives: To study incidence of Influenza pneumonia and describe clinical presenta tions and outcomes of Influenza pneumonia among hospitalized children.
Methods: This is cross-sectional descriptive study enrolled children 0-15 years of age, who were admitted during January 1, 2009 through December 31, 2009 due to community-acquired pneumonia. These patients were evaluated for the clinical presentations and the presence of common viral pathogens. Nasopharyngeal aspirate were examined by Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) for viruses.
Results: One hundred forty eight hospitalized children with CAP were enrolled, viral pathogens were identified in 20.94% of cases. Influenza virus and RSV were detected in 14 cases(9.45%) and 18 cases(12.16%) respectively. Median age of Influenza pneumonia patients was 3.2 years (range 4 months to 14.7 years). The most frequent signs of Influenza pneumonia were fever(100%), cough (85.7%) and dyspnea (85.7%). Of these children, 35.7% had at least one underlying disease. Crepitation, rhonchi and wheezing were found in most of patients (92.9%). The median duration of hospitalization was 5.8 days. No anyone of these patients was dead.
Conclusions: Influenza is the significant cause of morbidity leading to hospitalization in children with CAP, particularly for those under 5 years of age. เท addition, Influenza virus is the only currently vaccine-preventable. The enhance use of Influenza vaccine has the potential to reduce the pediatric morbidity from CAP.
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References
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