Gastrointestinal Stromal Tumors in Surin Hospital 2007-2008 : CT findings
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Abstract
Objective: To report the CT appearances of primary and metastatic gastrointestinal stromal tumors (GIST)
Design: Descriptive study
Study time: January 2007-December 2008
Method: The clinical and CT findings of 4 patients with histological and immuno histochemical (IHC) diagnosis of GIST were reviewed. The CT findings were assessed for location, size, enhancement characteristics, and pattern of metastasis.
Result:
: Clinical features
The population consisted of 2 men and 2 women, age range about 20-74 years old (mean age 46 years). Most of patients presented with Abdominal pain and 3 of them have gastrointestinal bleeding and anemia.
: CT features
The tumors were gastric (n=2), enteric (n=1) and mesentery, without Involvement of bowel (n=1). Primary tumors were endophytic and exophytic 50%, aneurysmal dilation of bowel 25% and large mass at mesentery 25%, larger than 5 cm. (6-10 cm.) 75%, and inhomogenous enhanment 100%. Metastatic disease was found in liver (n=1) and mesentery (n=1)
Conclusion: GIST is a new classification for a group of mesenchymal tomurs that predominantly exhibit an altered oncogene, KIT (CD 117). These tumors are different in behavior and immunology from the better known smooth muscle tumors of the gastrointestinal tract. Radiologist can often predict the correct diagnosis at presentation by the appearance of a large endophytic and exophytic bowel mass, which may show necrosis or hemorrhage. Like lymphoma, GIST can also show aneurysmal diratation of bowel. Metastasis were most commonly to the liver and seeding in peritoneal cavity (mesentery, omentum, peritoneum).
Key words: CT findings, GIST
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References
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