Clinical Manifestations of Malaria in Buriram Hospital 2005-2008
Article Sidebar
Main Article Content
Abstract
Background: Malaria remains one of the world’s major health problems, particularly in the topics and also found around the boundary of Thailand. There are many unusual manifestations and difficulties in early diagnosis.
Objective: To study the manifestations of malaria and laboratory findings for assisting in diagnosis.
Research design: Retrospective Descriptive Study
Patients: The patients who were diagnosed with malaria and treated at the Department of Medicine, Buriram Hospital.
Methods: Data from medical records during 1st October 2005 to 30th September 2008 were collected and demographic data, clinical data and laboratory profiles of all patients were analyzed.
Results: Thirty-nine patients (male 33 cases, female 6 cases) were enrolled. The median age was 36.62 years (range 16-73 years). There were 35 Thai (89.74%) and 4 Foreign Laborers (10.26%). 28 patients lived in Buriram province which 24 patients lived in the rural area outside of Buriram city and 7 patients lived in other provinces. Most were soldiers (35.90%), laborers (23.08%) and farmers (20.51%). p. falciparum infection was found in 20 patients (51.28%), p. vivax was found in 16 patients (41.03%) and mixed infection was found in 3 patients (7.69%). Manifestations of malaria were fever (100%), chills (89.74%) and headache (69.23%). Anemia, thrombocytopenia and hyperbilirubinemia were also found in most of patients. The complications of malaria were acute renal failure (10.26%), cerebral malaria (7.69%), respiratory failure (5.13%) and death (5.13%).
Conclusions: Clinical manifestations of malaria in Buriram Hospital were unspecific manifestations, therefore taking history included past medical illness, habitation and travels in the province around the border of Thailand and in the risk area of malaria infection. And using laboratory findings for differential diagnosis of malaria especially in soldiers who worked around the boundary of Thailand-Cambodia and Thailand-Myanmar and in foreign laborers.
Key words: Malaria, Clinical manifestations, Foreign Laborer
Article Details
References
2. World Malaria Report 2008. Available from:URL: https://www.who.int/malaria/ wmr2008/
3. สรุปรายงานการเฝ้าระวังโรค 2550 Availa- blefrom:URL:https://203.157.15.4/annual/ ANNUAL2550/Partl/Annual_ MenuPartl.html. : 23-26.
4. Echeverri M, Tobon A, Alvarez G, Carmona J, Blair S. Clinical and laboratory findings of Plasmodium vivax malaria in Columbia, 2001. Rev Inst Med Trop S Paulo 2003;45(1):29-34.
5. Sorrabjee JS. Haematological changes in malaria. Bombay Hosp J 1996;38;5-8.
6. Krause PJ. Malaria. In: Kliegman Robert M., Behrman Richard E„ Jenson Hal B., Stanton Bonita F„ edited. Nelson Textbook of Pediatric. 18th. ed. Philadelphia : Saunders, 2007:1477-85.
7. Kurtzhals JA, Rodrigues O, Addae M, Commey JO, Nkrumah FK, Hviid L. Reversible suppression of bone marrow response to erythropoietin in Plasmodium falciparum malaria. Brit J Hemat 1997;97:169-74.
8. White NJ, Looareesuwan S. Cerebral malaria. Kennedy PGE, Johnson RT, edited. Infections of the Nervous System. London: Butterworths, 1987:118-44.
9. Barsoum R, Sitprija V. Tropical nephrology. In: Schrier RW, Gottaschalk CW, edited. Diseases of the Kidney, 6th ed Boston : Little Brown & Co, 1996;2221-68.
10. Sitprija V. Nephropathy in falciparum malaria. Kidney Int 1998;34:867-77.
11. Looareesuwan S, White NJ, Chittamas S, Bunnag D, Harinasuta T. High rate of Plasmodium vivax relapse following treatment of falciparin malaria in Thailand. Lancet 1987;7;2(8567):1052-5.
