Pterygium Excision with Mitomy cin C (0.005%) in Sisaket Hospital

Main Article Content

Patcharee Sinithvarakul

Abstract

Objective: To study in recurrence rate and complications of pterygium excision with intraoperative low dose mitomycin c (0.005%) application
Method: This study was 2-year-retrospective in 252 primary single-headed pterygium patients since October 2002 to September 2004. All patients underwent excision of pterygium with intraoperative low dose mitomycin c (0.005%) application 30 seconds by one ophthalmologist. We studied in age, sex, recurrence rate and post-operative complications.
Results: 180 patients (71.4%) had followed up less than 6 months. In this group 6 patients have had recurrence. 72 patients (28.6%) had followed up more than 6 months. In this group were 14 male (19.4%) and 58 female (80.56%). The average age was 60.27 years (range 38-80 years) and the average follow up time was 16.5 months. The recurrence rate was 9.72%. No severe complications had been occurred.
Conclusion: Excision of pterygium with intraoperative low dose mitomycin c (0.005%) application appear to have low recurrence rate and safe.
Key words: Low dose mitomycin c (0.005%), Pterygium excision, Recurrence rates, Complications

Article Details

How to Cite
Sinithvarakul, P. (2018). Pterygium Excision with Mitomy cin C (0.005%) in Sisaket Hospital. MEDICAL JOURNAL OF SISAKET SURIN BURIRAM HOSPITALS, 23(2), 651–656. retrieved from https://he02.tci-thaijo.org/index.php/MJSSBH/article/view/152155
Section
Original Articles

References

1. Rubinfeld RS, Stein RM. Topical mitomycin c for pterygia : is single application appropriate? Ophthalmic Surg Lasers 1997;28(8):662-9.

2. Caliskan S, Orhan M, Irkec M. Intrao­perative and postoperative use of mitomycin c in the treatment of primary pterygium. Ophthalmic Surg Lasers 1996;27(7):600-4.

3. Frucht-pery J, Siganos CS, Ilsa M. Intraoperative application of topical mitomycin c for pterygium surgery. Ophthalmology 1996;103(4):674-7.

4. Mahar PS. Conjunctival autograft versus topical mitomycin c in treatment of pterygium. Eye 1997;11(Pt6):790-2.

5. Manning CA, Kloess PM, Diaz MD, Yee RW. Intraoperative mitomycin in primary pterygium excision. A prospective, randomized trial. Ophthalmology 1997;104(5):844-8.

6. Panda A, Das GK, Tuli SW, Kumar A. Randomized trial of intraoperative mitomycin c in surgery for pterygium. Am J Ophthalmol 1998;125(1):59-63.

7. Helal M, Messiha N, Amayem A, el-Maghraby A, Elsherif z, Dabees M. Intraoperative mitomycin c versus postoperative topical mitomycin c drops for the treatment of pterygium. Ophthalmic Surg Lasers 1996;27(8):674-8.

8. Prabhasawat P, Barton K, Burkett G, Tseng SC. Comparison of conjunctival autografts, amniotic membrane grafts, a primary closure for pterygium excision. Ophthalmology 1997;104(6):974-85.

9. Tan DT, Chee SP, Dear KB, Lim AS. Effect of pterygium morphology on pterygium recurrence in controlled trial comparing conjunctival autografting with bare sclera excision. Arch Ophthalmol 1997;115(10):1235-40.

10. Figueiredo RS, Cohen EJ, Gomes JA, Rapuano CJ, Laibson PR. Conjunctival autograft for pterygium surgery : how well dose it prevent recurrence? Ophthalmic Surg Lasers 1997;28(2):99-104.

11. Rachmiel R, Leiba H, Levatovsky S. Results of treatment with topical mitomycin c 0.02% following excision of primary pterygium. Br J ophthalmol 1995;79:233-6.

12. Frucht-Pery J, Lisar M, Hemo I. Single dosage of mitomycin c for prevention of recurrent pterygium : preliminary report. Cornea 1994;13:411-3.

13. Wan Norliza WM, Raihan IS, Azwa JA, Ibrahim M. Scleral melting 16 years after Pterygium excision with topical mitomycin c therapy. Cont Lens Anterior Eye 2006;29(4):165-7.

14. Tarr KH, Constable IJ. Late complications of pterygium treatment. Br J Ophthalmol 1980;64:496-505.

15. Schultze J, Hinrichs M, Kimming B. The results of strontium-90 contact therapy to prevent the recurrence of pterygium. Strahlenther Onkol 1996;172(8):417-21.

16. Wesberry JM Jr, Wesberry JM Sr. Optimal use of beta irradiation in the treatment of pterygia. South Med J 1993;86(6):633-7.

17. Moriarty AP, Crawford GJ, Mcallister IL, Constable IJ. Severe corneoscleral infection. A complication of beta irradiation scleral nacrosis following pterygium excision. Arch Ophthalmol 1993;111(7):947-51.

18. Lin CP, Shih MH, Tsai MC. Clinical experience of infectious scleral ulceration : a complication of pterygium operation. Br J Ophthalmol 1997;81(11):980-3.

19. Ma DH, See LC, Liau SB, Tsai RJ. Amniotic membrane graft for primary pterygium : comparison with conjunctival autograft and topical mitomycin C treatment. Br J Ophthalmol 2000:84(9):973-8.